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The Second Act with Michael and John

Michael Newborn, John Ballenger

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Wekelijks
 
Join hosts Michael (tech veteran and former product leader) and John (ret. USMC officer and Marine One pilot) on 'The Second Act' podcast, where ordinary people with extraordinary stories share their unique journeys in life's second act. From corporate executives to military veterans, consultants to entrepreneurs, the podcast delves into the diverse backgrounds and inspiring transformations of guests to highlight the power of grit, persistence, perspective, purpose and community.
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Michael’s Naturopathy Today

Michael Schwartz, ND

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Maandelijks
 
Naturopathy Today helps you find nature’s path to health and wellness. Hosts Dr. Michael Schwartz, ND and Steve Lankford are your guides on a journey to good health using wholistic naturopathic principles. Join them on a voyage to excellent health on all levels. New episodes every Monday. Hosts: Michael Schwartz, ND and Steve Lankford Contact: DrM@michaelshealth.com Design, Production, Editing and Voiceover: S. Phillips Music: Lauren Duski
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This podcast from NEJM Resident 360 takes a deep dive into key topics with expert clinicians and educators. As we explore the details of pathophysiology and critique the evidence behind clinical practice, these conversations are intended to give you better understanding of the topic and greater confidence when treating your patients.
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The Genetics Podcast

Sano Genetics

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Exploring all things genetics. Dr Patrick Short, University of Cambridge alumnus and CEO of Sano Genetics, analyses the science, interviews the experts, and discusses the latest findings and breakthroughs in genetic research. To find out more about Sano Genetics and its mission to accelerate the future of precision medicine visit: www.sanogenetics.com
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The Household Health Podcast with Michael Heuninckx RN-BSN

A weekly podcast empowering listeners to take an active role in the Health of their entire Household!

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The Household Health Podcast is a weekly podcast that is dedicated to delivering quality healthcare information and education to promote a healthy Household. Managing the health of your Household is a 24/7, 7 day a week, 365 days a year job. No matter how large the Household is, living a healthy life is not easy. It truly is a journey and one that no one should walk alone in. In episodes of The Household Health Podcast, interview are conducted with different healthcare professionals that hav ...
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Interviews with authors of Rational Clinical Examination systematic reviews in JAMA about the accuracy of the medical history, physical examination, and laboratory testing for the diagnosis of common medical conditions. JAMAevidence is an evidence-based medicine (EBM) resource created and maintained by JAMA Network to promote the use of EBM to improve patient care.
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show series
 
0:00 Intro to The Genetics Podcast 01:00 Welcome to Martin 01:35 How a particularly large Indian meal resulted in a book about intermittent fasting and the biology of ageing 05:10 The biological mechanisms behind intermittent fasting, and whether it’s been established to extend life expectancy in humans. 10:13 What we know (and what we don’t) about…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Tony J. Liles linkedin.com/in/tony-j-liles/ Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Apple: h…
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Tony 02:00 What Tony was expecting going into the role of CEO at UK Biocentre, and how the COVID-19 pandemic changed his plans 03:38 Receiving a phone call from the UK government in March 2020 asking the UK Biocentre to stop all of its projects and focus on sequencing COVID-19 samples 05:12 The UK…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Kasey Stewart (Bad Mouth Candy) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Apple: https://podca…
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0:00 Intro 2:00 Mike’s career prior to the Million Veteran Program (MVP), how Mike got to work on MVP, and important milestones in the project's evolution 8:30 Future goals for the Million Veteran Program in expanding and diversifying the research cohort 11:00 The roles of various omics in advancing the project's development 14:30 The most meaningf…
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Scott 01:55 Scott’s career highlights to date, ranging from epidemiology to the genetics of asthma and chronic obstructive pulmonary disease (COPD) 04:56 How and why Scott decided to transition into genetics 06:30 The advances in our understanding of the genetics of asthma and COPD over the past 2…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Terra Scott (https://www.linkedin.com/in/terra-scott) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422…
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Austin 01:42 What is aging and how should we think about it? 03:50 Discussion of Austin’s recent breakthrough paper on aging, including the questions he set out to answer, and the outcomes of the research 06:32 How Austin’s work focuses on using large-scale population proteomics data to create acc…
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Daniel 02:04 Defining rare disease in the age of personalized medicine 04:57 Key touchpoints with the Medicines and Healthcare products Regulatory Agency (MHRA) when developing a new medicine 09:27 Improvements over the course of Daniel’s career when it comes to incentivizing and making the path t…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Samantha Bell linkedin.com/in/bellsamantha001 Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Apple:…
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0:00 Introduction 1:40 A recurrent de novo mutation in a noncoding region of a small nucleolar RNA gene that has been identified as one of the most common causes of neurodevelopmental disorders This pathogenic variant escaped notice for years because it was not located in a protein coding region of the genome It now shows potential as a target for …
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Pavel Bosovik linkedin.com/in/pavel-bosovik the27north.com Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb63…
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Jakob and background on Pheiron 02:14 What made Jakob decide to start Pheiron, what the company does, and how his scientific background inspired him to found a start-up 5:24 Jakob’s excitement and inspiration around the power and potential of machine learning 07:07 Cardiology and heart failure as …
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Joshua Becker facebook.com/becomingminimalist linkedin.com/in/becoming-minimalist becomingminimalist.com Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify…
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0:00 Introduction 1:40 Andrea’s background and how she got into the field of genetics, neuroimaging, and metabolic disorders 4:00 Insights into Andrea’s clinical practice, including the diverse families and patients she serves and her approach to clinical decision-making 6:30 How genetics and genomics have changed the diagnostic journey in the last…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Ross Dickman HireHeroesusa.org linkedin.com/in/rossdickman/ Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb6…
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Lori Orlando 03:00 Lori’s career: From mathematical modelling to genetics and family history 05:11 The study that revealed 20% of the general population is at a higher risk of disease than average and needs preventative care 07:36 The first five diseases that Lori started analysing through informa…
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0:00 Intro to The Genetics Podcast 1:00 Welcome to Ben Goldacre 02:22 Ben’s open data projects at the Bennett Institute and the challenges they aim to tackle 04:03 Using Electronic Health Records (EHR) to help the National Health Service improve care 06:18 The importance of software development within healthcare data and how to manage salary scales…
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0:00 Intro to The Genetics Podcast. 01:00 Welcome to Michelle. 02:00 Sstop codon diseases and how are they characterised 03:45 Diseases caused by premature stop codons in haploinsufficient genes. 04:35 The role of transfer RNA technology in finding solutions for premature stop codon diseases. 06:16 How Alltrna is engineering tRNAs which can bind to…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Maurice Philogene (https://www.linkedin.com/in/mauricephilogene/) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Ben Nelson (https://www.linkedin.com/in/bennelson303/) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c42…
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0:00 Introduction 1:45 Almut’s research experience, including two recent publications on genome-scale metabolic reconstruction human microorganisms Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Nick Rotola (Founder & CEO of WE3 Group, Inc.) https://www.linkedin.com/in/nick-rotola-b87776149 Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/sho…
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0:00 Intro 1:30 Mavis’ career arc, from starting as a midwife to researching medical innovation and technology with an emphasis on advocacy and equity 7:00 Systemic issues that are easily overlooked in medical research and advancements Webinar: Participant Diversity: Increasing the Impact of Biomedical Research Webinar 10:00 Addressing Eurocentrici…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: John Macaskill https://www.linkedin.com/in/jonmacaskill/ Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c…
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0:00 Introduction 2:00 Allison’s personal journey to researching epilepsy and ring chromosome 20 syndrome 4:00 Biggest challenges families face with ring chromosome 20 syndrome 11:00 Incidence and prevalence of r(20) syndrome, and how we can improve data reliability 21:00 Applying next generation sequencing to r(20) syndrome gene research 29:00 Eng…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Alvin Cooper III (Founder of CStyled) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Apple: https:/…
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0:00 Introduction 1:30 Ingrid’s initial interests in genetics, paediatrics, and newborn screening 2:45 How the original BabySeq project, a pioneering newborn sequencing program got started, how it’s going, and the launch of BabySeq2 8:45 Lessons from BabySeq1 and goals for BabySeq2 10:30 Potential societal and long-term considerations for those inv…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Lindsey Nehls https://www.elevateleadership.com/ Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a App…
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0:00 Introduction 1:00 The backstory of how Kira first started DNA Today in 2012, when she was still in high school! 3:30 Some of Kira’s favourite topics she has discussed on DNA Today, including the legacy of Henrietta Lacks, and the story of a Glee actress with down syndrome 10:00 Kira’s best practices for podcasting, from over 10 years of experi…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Jacob Rupp (https://www.linkedin.com/in/jacobrupp/) BusinessLift (https://www.businesslift.com/) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/sho…
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Dislocated hips in newborns can lead to complex surgery, interruption to family life, and premature osteoarthritis. Daniel Perry, MBChb(Hons), PhD, of Alder Hey Children's Hospital, University of Liverpool, discusses the clinical diagnosis of dislocated hips in newborns with JAMA Associate Editor David Simel, MD, MHS. Related Content: Does This Inf…
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0:00 Introduction 2:00 The value of an English Literature degree in designing and analysing research studies in medicine 3:45 Emma’s entrance to pharmacogenomics and her transition from practising physician to genetics research 6:00 How the East London Genes and Health program is increasing representation of diverse populations, namely South Asians…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Harley Blakeman (https://www.linkedin.com/in/harley-blakeman/) Honest Jobs (https://www.honestjobs.com/) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify…
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0:00 Introduction 1:00 George’s upcoming big projects, including developing full recycling, renewing energy, creating bioweather maps, and harnessing citizen science 6:45 Progress in engineering viral resistance in humans, including thoughts from pre- and post- pandemic 11:00 A swapped genetic code that prevents viral infections and gene transfer b…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Marcus Long (linkedin.com/in/marcus-long-22278391) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a A…
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0:00 Intro 0:40 Jake’s experiences as a serial entrepreneur starting five companies with a basis in genomic science 5:30 Opportunities for research and drug development in the realm of somatic science 9:20 Somatic evolution and how it provides valuable insights into disease mechanisms 12:30 Advantages and disadvantages of studying germline genome-w…
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In this episode of Curbside Consults, Dr. Andrew Dwyer, Director of Psychometrics at the American Board of Pediatrics (ABP), joins Mridula Nadamuni, former editorial fellow, to discuss the process of creating and administering pediatric board examinations. Andy Dwyer holds a PhD in educational psychology and an MS in statistics from the University …
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Todd Lancaster (https://www.linkedin.com/in/1toddlancaster) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb6…
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Show Notes: 0:00 Introduction 1:20 How polydactyl mutations can inform research on non-coding variant mechanisms The importance of low-affinity binding between transcription factors and targets How these lessons can help us improve our understanding of drug and target discovery See Veera’s January round-up for more information: https://www.gwasstor…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Apple: https://podcasts.apple.com/us/podcast/the-second-act…
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0:00 Introduction 0:45 Jean’s personal experiences with family members with genetic ALS 10:00 Jean’s thoughts on the barriers and facilitators to providing treatment for those with genetic ALS 13:20 Insights into C9orf72, a common genetic determinant of ALS, and how it can also be associated with FTD 16:10 Jean’s experiences as an active advocate f…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Martin Skea linkedin.com/in/martin-skea/ https://eit.europa.eu/news-events/news/eit-community-new-european-bauhaus-catalyse-programme-looking-socially-innovative Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me"…
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0:00 Introduction 1:05 Insights into the PD GENEration’s (a programme from the Parkinson's Foundation) milestones and progress points for the upcoming year 3:30 The shifting attitudes and perspectives of neurologists and healthcare workers at the PD GENEration 5:50 Insights into Nacho’s work with the genetics of Parkinson’s disease 10:20 Barriers a…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Michelle "Mace" Curran michaelandjohn.com/mace instagram.com/mace_curran linkedin.com/in/macecurran/ Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com…
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0:00 Intro 0:25 Mazen’s lifelong commitment to furthering the field of precision medicine in liver disease research, fueled by a personal connection of his grandmother developing MASH cirrhosis 2:30 Breakthroughs in the field of metabolic dysfunction-associated steatotic liver disease (MASLD) since the beginning of Mazen’s career 5:30 The potential…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Erik Thompson (https://thompsonleadership.com/) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Appl…
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0:00 Introduction 0:25 Julia’s personal experience with ultra-rare diseases within her family 10:25 The importance of increasing accessibility to genetic testing across populations to learn more about ultra-rare diseases 14:00 The origin story of Rare Trait Hope Fund 23:50 Current research and next steps in developing potential gene therapies for a…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Isaac Lee (linkedin.com/in/isaaclee1) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Apple: https:/…
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0:00 Introduction 1:25 How Lord O’Shaughnessy became involved in scientific policy making and his path to writing the UK Commercial Clinical Trials Review. 04:05 How Lord O’Shaughnessy pivoted from education to a focus on life sciences 06:38 The biggest challenges Lord O’Shaughnessy faced during his time as Parliamentary Under Secretary for Health …
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