How can we, humans, look at our relationship to nature differently? In season three of Going Wild, on top of stories about animals, we invite you to journey through the entire ecological web — from the tiniest of life forms to apex predators — alongside the scientists, activists and adventurers who study it. Wildlife biologist and host Dr. Rae Wynn-Grant has been studying wild animals in their natural habitats all over the world for years. Our award-winning podcast takes you inside the hidde ...
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EP 127: Insights into precision medicine, fatty liver disease, and minimally invasive diagnostic tools with Dr. Mazen Noureddin
MP3•Thuis aflevering
Manage episode 408103462 series 2631947
Inhoud geleverd door Sano Genetics. Alle podcastinhoud, inclusief afleveringen, afbeeldingen en podcastbeschrijvingen, wordt rechtstreeks geüpload en geleverd door Sano Genetics of hun podcastplatformpartner. Als u denkt dat iemand uw auteursrechtelijk beschermde werk zonder uw toestemming gebruikt, kunt u het hier beschreven proces https://nl.player.fm/legal volgen.
0:00 Intro
0:25 Mazen’s lifelong commitment to furthering the field of precision medicine in liver disease research, fueled by a personal connection of his grandmother developing MASH cirrhosis
2:30 Breakthroughs in the field of metabolic dysfunction-associated steatotic liver disease (MASLD) since the beginning of Mazen’s career
5:30 The potential impact of Resmetirom, a new drug that could treat MASLD and MASH cirrhosis
8:45 Significant takeaways from 40+ investigational clinical studies of novel treatments for MASLD/MASH
12:00 Alternatives to biopsies and potential tools for early, non-invasive diagnosis
19:00 Genetic determinants and risk factors for fatty liver disease
20:30 How Mazen uses genetic testing in the clinic for his patients
25:50 The impact of “miracle” weight loss drugs such as GLP-1s on patients with liver disease
29:30 The importance of early intervention to prevent late-stage cirrhosis
33:00 How to tailor treatment to consider environmental and epigenetic factors that impact genetic penetrance for liver disease
36:00 Potential links between metabolism and neurodegenerative conditions
39:00 Upcoming developments in MASLD and MASH research
41:00 Mazen’s relationship with his father, both as a dad and as a teacher
176 afleveringen
MP3•Thuis aflevering
Manage episode 408103462 series 2631947
Inhoud geleverd door Sano Genetics. Alle podcastinhoud, inclusief afleveringen, afbeeldingen en podcastbeschrijvingen, wordt rechtstreeks geüpload en geleverd door Sano Genetics of hun podcastplatformpartner. Als u denkt dat iemand uw auteursrechtelijk beschermde werk zonder uw toestemming gebruikt, kunt u het hier beschreven proces https://nl.player.fm/legal volgen.
0:00 Intro
0:25 Mazen’s lifelong commitment to furthering the field of precision medicine in liver disease research, fueled by a personal connection of his grandmother developing MASH cirrhosis
2:30 Breakthroughs in the field of metabolic dysfunction-associated steatotic liver disease (MASLD) since the beginning of Mazen’s career
5:30 The potential impact of Resmetirom, a new drug that could treat MASLD and MASH cirrhosis
8:45 Significant takeaways from 40+ investigational clinical studies of novel treatments for MASLD/MASH
12:00 Alternatives to biopsies and potential tools for early, non-invasive diagnosis
19:00 Genetic determinants and risk factors for fatty liver disease
20:30 How Mazen uses genetic testing in the clinic for his patients
25:50 The impact of “miracle” weight loss drugs such as GLP-1s on patients with liver disease
29:30 The importance of early intervention to prevent late-stage cirrhosis
33:00 How to tailor treatment to consider environmental and epigenetic factors that impact genetic penetrance for liver disease
36:00 Potential links between metabolism and neurodegenerative conditions
39:00 Upcoming developments in MASLD and MASH research
41:00 Mazen’s relationship with his father, both as a dad and as a teacher
176 afleveringen
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