Spermidine for Longevity with Leslie Kenny

Biohacker's Podcast

In this episode, Leslie Kenny joins Dr. Olli Sovijärvi to discuss the various health benefits of Spermidine, its natural food sources, and recommended supplementation.

Leslie Kenny is an Oxford-based entrepreneur born in California and a graduate of Berkeley and Harvard Business School. In her 30s, her life changed dramatically when she was diagnosed with an array of autoimmune conditions - lupus, rheumatoid arthritis and hypothyroidism. Her doctors told her there was no cure and that they could only be managed with strong immunosuppressants.

Raised with the mentality that it's best to work with your body's innate wisdom to heal itself, Leslie chose to instead support her immune system in its natural abilities. As well as becoming a certified health coach, Leslie began helping scientists at leading European universities, including the University of Oxford, to raise money for their health discoveries.

It was at a meeting with one such scientist that she learned of a compound called spermidine. Because it was a natural and food-derived compound, not a drug that would bring in more money, no one was interested in promoting it. So with the support of esteemed University of Oxford scientists and doctors that make up our Board of Scientific and Clinical Advisors, Leslie launched Oxford Healthspan with its flagship product, the plant-derived spermidine supplement Primeadine®.

Learn more about Leslie and Oxford Healthspan at https://www.oxfordhealthspan.com!

This conversation was recorded in November 2023.

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Key moments and takeaways:

00:00 Introduction by Dr. Olli Sovijärvi

01:25 Spermidine basics

02:16 Micronutrients in semen

02:53 Babies need spermidine, mothers lose hair

04:02 It's not just about SAM-e

05:41 Spermidine for recovery

07:46 Natural food sources

08:58 A healthy gut is crucial

09:37 Bacteria that make Spermidine

10:32 Top 3 food sources

14:00 Chlorella as a source of spermidine

15:18 The optimal dose

17:02 Avoiding anti-nutrient dense foods, alternative diets

20:30 Long term effects, hallmarks of aging

22:39 The Goldilocks Zone and fertility

25:50 Other benefits of spermidine & Primeadine

28:00 The Salvage Pathway of polyamines

29:41 When should you start supplementing?