E137: Hannah Bargh-Dawson - Using Ultrasound to Stimulate Microbubbles for Radio-Sensitisation

Rad Chat

Naman Julka-Anderson and Jo McNamara catch up with Hannah Bargh-Dawson as part of Education and Workforce Development series (part 51).

Discussion about Hannah’s career, PhD research and the potential of using ultrasound to stimulate microbubbles for radio-sensitisation in preclinical research.

To use this podcast as CPD, look at these reflection points:

1) consider the possibilities and limitations of microbubbles in radio-sensitisation.

2) reflect on who you look to for mentorship for your development.

3) consider how you can learn from your failures in your practice.

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Links from podcast:

A guide to UK PhDs: https://www.phdportal.com/countries/30/united-kingdom.html

Institute of Cancer Research (ICR) fully-funded PhD projects: https://www.icr.ac.uk/studying-and-training/phds-for-science-graduates/phd-studentship-projects

Acoustic Cluster Therapy: https://www.icr.ac.uk/news-archive/world-first-treatment-with-acoustic-cluster-therapy-to-improve-chemotherapy-delivery

Tumour-liquifying microbubbles and immune cell tracking: UK’s first convergence science centre officially launches: https://www.icr.ac.uk/news-archive/tumour-liquifying-microbubbles-and-immune-cell-tracking-uk-s-first-convergence-science-centre-officially-launches

The Cancer Research UK Convergence Science Centre: https://www.icr.ac.uk/our-research/centres-and-collaborations/strategic-collaborations/convergence-science-centre

NC3R link: https://nc3rs.org.uk/

Research articles:

Tumor radiation response enhancement by acoustical stimulation of the vasculature:https://www.pnas.org/doi/suppl/10.1073/pnas.1200053109

A study combining microbubble-mediated focused ultrasound and radiation therapy in the healthy rat brain and a F98 glioma model: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10899261/

Radiation enhancement using focussed ultrasound-stimulated microbubbles for breast cancer: A Phase 1 clinical trial: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11146716/

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