Engineering Better Health: The Mind-Gut Connection with Dr Emeran Mayer

The Happier Life Project

The gut-brain connection is a two-way communication system between your gut and brain. It’s an intricate network of nerve cells, chemicals, and microbes and explains why your stomach produces juices when you think about food, and why stress can cause stomach cramps or a churning feeling. This connection links your central nervous system (CNS), including the brain, with the enteric nervous system (ENS) in your gut. Often referred to as the "second brain," the ENS significantly impacts (and creates a link between) gut health and mental health.

Phrases like "gut-wrenching" or "butterflies in the stomach" illustrate this connection further, as our digestive system responds to emotions such as anger, anxiety, sadness, nervousness and happiness. Consequently, gastrointestinal issues can both cause and result from stress, anxiety, or depression; demonstrating the close relationship between the brain and the digestive system.

So if we improve our gut health, we better our mental health. And in return, better mental health can alleviate certain digestive issues and lead to stronger gut health.

Dr Emeran Mayer is a leading expert on the mind-gut connection. A world renowned and award winning gastroenterologist, neuroscientist and Distinguished Research Professor in the Departments of Medicine, Physiology and Psychiatry at the David Geffen School of Medicine at UCLA, Dr Emeran has accumulated 35 years of research on the clinical and neurobiological relationship between the digestive system and the nervous system.

Dr Emeran is also a best selling author of the books “The Mind-Gut Connection”, “The Mind-Gut Immune Connection” and the recipe book “Interconnected Plates”. His work primarily explores the complex interactions between the gut and the brain, particularly how these interactions impact conditions like irritable bowel syndrome (IBS), chronic pain, and emotional well-being.

In this episode of The Happier Life Project, Dr Emeran simplifies how the brain and gut communicate. He discusses the influence food has on our emotions and expresses his frustrations with ultra-processed food suppliers, for producing harmful and addictive products. Dr Emeran also explains the science behind the Mediterranean diet as a model for optimal gut health and shares research on the benefits of following a restricted eating window. By not not having food in your stomach 24 hours a day, you allow your gut to cleanse itself of unwanted bacteria in the small intestine and activate its 'housekeeper' function.

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