Bridging the knowledge-practice gap in tuberculosis management in Indonesia and Mongolia

Global Child and Adolescent Health

In this episode Professor Steve Graham discusses bridging the knowledge-practice gap in tuberculosis management with Dr Trisasi Lestari, Universitas Gadjah Mada, Indonesia, and Dr Bazarragchaa Tsogt, Mongolian Anti-Tuberculosis Coalition, Mongolia.

Dr Trisasi Lestari is a tuberculosis (TB) researcher at the Center for Tropical Medicine at the University of Gadjah Mada, Indonesia. Dr Lestari is also a PhD candidate at Menzies School of Health Research at Charles Darwin University.

Dr Bazarragchaa Tsogt, Mongolian Anti-Tuberculosis Coalition.

Professor Steve Graham is a Co-Chair for Melbourne Children's Global Health, Professor of International Child Health, University of Melbourne and Group Leader, International Child Health, Murdoch Children's Research Institute.

Further reading:

1. du Preez K, Gabardo BMA, Kabra SK, Triasih R, Lestari T, Kal M, Tsogt B, Dorj G, Purev E, Nguyen TA, et al. Priority Activities in Child and Adolescent Tuberculosis to Close the Policy-Practice Gap in Low- and Middle-Income Countries. Pathogens. 2022; 11(2):196. https://doi.org/10.3390/pathogens11020196
2. Lestari T, Kamaludin, Lowbridge C, Kenangalem E, Poespoprodjo JR, Graham SM, Ralph AP. Impacts of tuberculosis services strengthening and the COVID-19 pandemic on case detection and treatment outcomes in Mimika District, Papua, Indonesia: 2014-2021. PLOS Glob Public Health. 2022 Sep 30;2(9):e0001114. doi: 10.1371/journal.pgph.0001114. PMID: 36962674; PMCID: PMC10021881.
3. Main S, Lestari T, Triasih R, Chan G, Davidson L, Majumdar S, Santoso D, Phung S, Laukkala J, Graham S, du Cros P, Ralph A. Training for Tuberculosis Elimination in Indonesia: Achievements, Reflections, and Potential for Impact. Trop Med Infect Dis. 2019 Jul 18;4(3):107. doi: 10.3390/tropicalmed4030107. PMID: 31323840; PMCID: PMC6789479.
4. Lestari T, Graham S, van den Boogard C, Triasih R, Poespoprodjo JR, Ubra RR, Kenangalem E, Mahendradhata Y, Anstey NM, Bailie RS, Ralph AP. Bridging the knowledge-practice gap in tuberculosis contact management in a high-burden setting: a mixed-methods protocol for a multicenter health system strengthening study. Implement Sci. 2019 Mar 19;14(1):31. doi: 10.1186/s13012-019-0870-x. PMID: 30890160; PMCID: PMC6425655.
5. South A, Dhesi P, Tweed CD, Tsogt B, Staples S, Tukvadze N, Dorj G, Zaca S, Sanikidze E, Purev N, Esmail H, Burgess R. Patients' priorities around drug-resistant tuberculosis treatment: A multi-national qualitative study from Mongolia, South Africa and Georgia. Glob Public Health. 2023 Jan;18(1):2234450. doi: 10.1080/17441692.2023.2234450. PMID: 37431789.
6. Nunn AJ, Phillips PPJ, Meredith SK, Chiang CY, Conradie F, Dalai D, van Deun A, Dat PT, Lan N, Master I, Mebrahtu T, Meressa D, Moodliar R, Ngubane N, Sanders K, Squire SB, Torrea G, Tsogt B, Rusen ID; STREAM Study Collaborators. A Trial of a Shorter Regimen for Rifampin-Resistant Tuberculosis. N Engl J Med. 2019 Mar 28;380(13):1201-1213. doi: 10.1056/NEJMoa1811867. Epub 2019 Mar 13. PMID: 30865791.
7. Goodall RL, Meredith SK, Nunn AJ, Bayissa A, Bhatnagar AK, Bronson G, Chiang CY, Conradie F, Gurumurthy M, Kirenga B, Kiria N, Meressa D, Moodliar R, Narendran G, Ngubane N, Rassool M, Sanders K, Solanki R, Squire SB, Torrea G, Tsogt B, Tudor E, Van Deun A, Rusen ID; STREAM study collaborators. Evaluation of two short standardised regimens for the treatment of rifampicin-resistant tuberculosis (STREAM stage 2): an open-label, multicentre, randomised, non-inferiority trial. Lancet. 2022 Nov 26;400(10366):1858-1868. doi: 10.1016/S0140-6736(22)02078-5. Epub 2022 Nov 8. Erratum in: Lancet. 2022 Nov 19;400(10365):1766. PMID: 36368336; PMCID: PMC7614824.