Health Discourse with Sakshi & Sushant- Episode 3

Genefitletics

100 million people in India are dealing with type 2 diabetes & counting! India is called Diabetic capital of the world. We have all science & technology & even healthcare to address range of chronic diseases including type 2 diabetes but still the number of Diabetic population seem to increase with current healthcare industry having no clue how to eradicate this epidemic Do you know why? The industry is too much focussed on managing type 2 diabetes through generic nutrition & pharmaceutical approach rather than going deep down to understand & decode hard to detect signals & asymptomatic molecular targets involved in onset & progression of this metabolic syndrome & now we have these new age health tech companies who are promoting diabetes reversal programs!Are these programs really worth it? Do they really reverse diabetes? Answer to these questions is NO . More so as none of these companies address 99% of our biology epigenetically- our microbiome It is important to understand the mechanics behind onset & progression of type 2 diabetes Imbalanced biology triggered by gut /oral microbial dysbiosis creates a situation where first fasting insulin spikes, then fasting glucose spikes & finally Hba1c spikes. The focus has to be to prevent fasting insulin from spiking. If you are suppressing Hba1c or blood glucose levels, the damage has been done. You are just suppressing these plasma level biomarkers. So what regulates insulin response. There are multiple molecules that come into play , produced both by gut & oral microbiome. The most important one that makes sure that glucose is not left in circulation & is transported into your cells for performing various biological processes is NITRIC OXIDE. Nitric oxide is produced via two pathways -Endothelial cells which line every single blood vessel. However our cells ability to produce NO reduces as we age. Oral Microbiome Certain microbes synthesises nitrate into nitrite which is precursor for NO production If you are not able to measure NO production & other relevant gut microbiome derived metabolites such as Butyrate, GLP-1, PYY, Fucose Pathway, LPS & more, you can never solve diabetes. Just think over it. Do you want to manage a condition you already have or would like to understand what makes me/going to make me develop a disease & how I can eliminate the chemicals involved in the disease before the disease onset.

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