We’ve all had a moment where we arrived at the grocery store and can’t remember passing any of the stoplights along the way. We’re halfway down an aisle and scrambling to remember what we even needed. Our mind is in overdrive trying to sort through our ever-growing to-do list. We’ve been there when just making it through the next task is hard. But the normal stresses of life aren’t the only thing YOU have to deal with. Nora McInerny hosts The Head Start: Embracing the Journey, a new podcast ...
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Dairy Causes Cancer To Metastasize?
MP3•Thuis aflevering
Manage episode 376170078 series 3072470
Inhoud geleverd door The Alpha Human Podcast. Alle podcastinhoud, inclusief afleveringen, afbeeldingen en podcastbeschrijvingen, wordt rechtstreeks geüpload en geleverd door The Alpha Human Podcast of hun podcastplatformpartner. Als u denkt dat iemand uw auteursrechtelijk beschermde werk zonder uw toestemming gebruikt, kunt u het hier beschreven proces https://nl.player.fm/legal volgen.
Disclaimer: The content of this podcast, and any information, advice, opinions or statements within it are not intended, and are not to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not disregard or delay in obtaining medical advice for any medical condition you may have, and you should seek the assistance of a healthcare professional for any such conditions, and always inform your doctor of any changes you make, or are thinking about making to your lifestyle. In this episode of the Alpha Human Podcast, Lawrence examines various interventional studies on the effects of dairy consumption on cancer progression and shares evidence suggesting that bovine milk, particularly its casein content, can lead to the metastasis of cancer. With that said, milk proteins have also been shown to possess anti-cancer properties as well and here we navigate this nuanced landscape, presenting both sides of the argument. Intriguingly, and beyond the milk protein debate, Lawrence raises a far larger concern with respect to dairy and cancer, an issue starker than the conjecture surrounding casein protein, and that is the problems related to extracellular vesicles (EVs) derived from milk—a concern that could reshape the way we think about dairy consumption for individuals dealing with cancer. The podcast explores a study that yielded unexpected results—while milk-derived EVs induced cellular senescence in cancer cells, reducing primary tumor size, they paradoxically accelerated cancer metastasis. This finding serves as a pivotal warning to those with cancer who might consider consuming dairy. Lawrence's analysis of this critical revelation underscores the importance of carefully evaluating dietary choices, especially for individuals navigating cancer, and making informed decisions based on the available evidence. Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis https://www.nature.com/articles/s41467-021-24273-8 β-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility https://www.ncbi.nlm.nih.gov/pmc/articles/PMC275444/ Promotion of Aberrant Crypt Foci and Cancer in Rat Colon by Thermolyzed Protein https://academic.oup.com/jnci/article-abstract/84/13/1026/985189 Milk Stimulates Growth of Prostate Cancer Cells in Culture https://www.tandfonline.com/doi/full/10.1080/01635581.2011.609306 A Milk Protein, Casein, as a Proliferation Promoting Factor in Prostate Cancer Cells https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166373/ The milk protein α-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507493/ Growth inhibitory effects of casein hydrolysates on human cancer cell lines https://pubmed.ncbi.nlm.nih.gov/20053315/ Casein and Peptides Derived from Casein as Antileukaemic Agents https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754885/ The Therapeutic Potential of Milk Extracellular Vesicles on Colorectal Cancer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224713/ Bovine milk-derived exosomes for drug delivery https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706492/ Camel Milk Modulates the Expression of Aryl Hydrocarbon Receptor-Regulated Genes, Cyp1a1, Nqo1, and Gsta1, in Murine hepatoma Hepa 1c1c7 Cells https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345340/
…
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60 afleveringen
MP3•Thuis aflevering
Manage episode 376170078 series 3072470
Inhoud geleverd door The Alpha Human Podcast. Alle podcastinhoud, inclusief afleveringen, afbeeldingen en podcastbeschrijvingen, wordt rechtstreeks geüpload en geleverd door The Alpha Human Podcast of hun podcastplatformpartner. Als u denkt dat iemand uw auteursrechtelijk beschermde werk zonder uw toestemming gebruikt, kunt u het hier beschreven proces https://nl.player.fm/legal volgen.
Disclaimer: The content of this podcast, and any information, advice, opinions or statements within it are not intended, and are not to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not disregard or delay in obtaining medical advice for any medical condition you may have, and you should seek the assistance of a healthcare professional for any such conditions, and always inform your doctor of any changes you make, or are thinking about making to your lifestyle. In this episode of the Alpha Human Podcast, Lawrence examines various interventional studies on the effects of dairy consumption on cancer progression and shares evidence suggesting that bovine milk, particularly its casein content, can lead to the metastasis of cancer. With that said, milk proteins have also been shown to possess anti-cancer properties as well and here we navigate this nuanced landscape, presenting both sides of the argument. Intriguingly, and beyond the milk protein debate, Lawrence raises a far larger concern with respect to dairy and cancer, an issue starker than the conjecture surrounding casein protein, and that is the problems related to extracellular vesicles (EVs) derived from milk—a concern that could reshape the way we think about dairy consumption for individuals dealing with cancer. The podcast explores a study that yielded unexpected results—while milk-derived EVs induced cellular senescence in cancer cells, reducing primary tumor size, they paradoxically accelerated cancer metastasis. This finding serves as a pivotal warning to those with cancer who might consider consuming dairy. Lawrence's analysis of this critical revelation underscores the importance of carefully evaluating dietary choices, especially for individuals navigating cancer, and making informed decisions based on the available evidence. Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis https://www.nature.com/articles/s41467-021-24273-8 β-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility https://www.ncbi.nlm.nih.gov/pmc/articles/PMC275444/ Promotion of Aberrant Crypt Foci and Cancer in Rat Colon by Thermolyzed Protein https://academic.oup.com/jnci/article-abstract/84/13/1026/985189 Milk Stimulates Growth of Prostate Cancer Cells in Culture https://www.tandfonline.com/doi/full/10.1080/01635581.2011.609306 A Milk Protein, Casein, as a Proliferation Promoting Factor in Prostate Cancer Cells https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166373/ The milk protein α-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507493/ Growth inhibitory effects of casein hydrolysates on human cancer cell lines https://pubmed.ncbi.nlm.nih.gov/20053315/ Casein and Peptides Derived from Casein as Antileukaemic Agents https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754885/ The Therapeutic Potential of Milk Extracellular Vesicles on Colorectal Cancer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224713/ Bovine milk-derived exosomes for drug delivery https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706492/ Camel Milk Modulates the Expression of Aryl Hydrocarbon Receptor-Regulated Genes, Cyp1a1, Nqo1, and Gsta1, in Murine hepatoma Hepa 1c1c7 Cells https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345340/
…
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