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Ep. 86: “Myeloid Cells” Featuring Dr. Kipp Weiskopf
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Guest:
Dr. Kipp Weiskopf is a Valhalla Fellow at the Whitehead Institute. His research focuses on unlocking the therapeutic potential of macrophages for the benefit of cancer patients. He talks about the role of macrophages in the tumor environment and how targeting the CD47/SIRPα axis can induce phagocytosis of cancer cells. He also discusses starting spin-off companies to advance cancer therapies.
Featured Products and Resources:
- Request your free copy of the ‘Human Immune Cytokines’ Wallchart
- The STEMdiff Monocyte Kit generates millions of monocytes ready for downstream assays or further development into macrophages or dendritic cells.
The Immunology Round Up
Organoids with an Immune Compartment – Researchers generated human intestinal immuno-organoids to investigate intestinal inflammation triggered by cancer-targeting biologics in patients.
Gene Repression in Tregs – The transcription factor Ikaros binds to Foxp3 to inhibit the expression of target genes in Tregs.
γδ T-Cell Antigen Receptor Structure – Scientists used cryo-electron microscopy to determine the structure of of the T-cell receptor found on the surface of γδ T cells.
Autoimmune Organ Damage – Tissue-resident NKp46+ innate lymphoid cells are crucial signal amplifiers of disease-associated macrophage expansion and epithelial cell injury in lupus nephritis.
Image courtesy of Dr. Kipp Weiskopf
115 afleveringen
Fetch error
Hmmm there seems to be a problem fetching this series right now. Last successful fetch was on December 18, 2024 00:38 ()
What now? This series will be checked again in the next day. If you believe it should be working, please verify the publisher's feed link below is valid and includes actual episode links. You can contact support to request the feed be immediately fetched.
Manage episode 436549757 series 2895470
Guest:
Dr. Kipp Weiskopf is a Valhalla Fellow at the Whitehead Institute. His research focuses on unlocking the therapeutic potential of macrophages for the benefit of cancer patients. He talks about the role of macrophages in the tumor environment and how targeting the CD47/SIRPα axis can induce phagocytosis of cancer cells. He also discusses starting spin-off companies to advance cancer therapies.
Featured Products and Resources:
- Request your free copy of the ‘Human Immune Cytokines’ Wallchart
- The STEMdiff Monocyte Kit generates millions of monocytes ready for downstream assays or further development into macrophages or dendritic cells.
The Immunology Round Up
Organoids with an Immune Compartment – Researchers generated human intestinal immuno-organoids to investigate intestinal inflammation triggered by cancer-targeting biologics in patients.
Gene Repression in Tregs – The transcription factor Ikaros binds to Foxp3 to inhibit the expression of target genes in Tregs.
γδ T-Cell Antigen Receptor Structure – Scientists used cryo-electron microscopy to determine the structure of of the T-cell receptor found on the surface of γδ T cells.
Autoimmune Organ Damage – Tissue-resident NKp46+ innate lymphoid cells are crucial signal amplifiers of disease-associated macrophage expansion and epithelial cell injury in lupus nephritis.
Image courtesy of Dr. Kipp Weiskopf
115 afleveringen
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