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EP 107: Integrating Genomics and Individualised Medicine into the Mayo Clinic Healthcare System with Dr. Konstantinos Lazaridis
MP3•Thuis aflevering
Manage episode 376935968 series 2631947
Inhoud geleverd door Sano Genetics. Alle podcastinhoud, inclusief afleveringen, afbeeldingen en podcastbeschrijvingen, wordt rechtstreeks geüpload en geleverd door Sano Genetics of hun podcastplatformpartner. Als u denkt dat iemand uw auteursrechtelijk beschermde werk zonder uw toestemming gebruikt, kunt u het hier beschreven proces https://nl.player.fm/legal volgen.
In this episode of The Genetics Podcast, we welcome Dr. Konstantinos Lazaridis, the Executive Director of the Center for Individualized Medicine at the Mayo Clinic. Tune in to learn about the impacts of genomics and individualised medicine on rare liver diseases and advanced cancers . Discover how the Mayo Clinic actively uses genomic testing, precision medicine, and environmental interventions to improve patient outcomes.
Timestamps:
0:00 Introduction
0:00 Introduction
0:32 Insights into the Center for Individualised Medicine at the Mayo Clinic, including the importance of predictive genomics, research in rare and undiagnosed diseases, and the integration of genomics into healthcare
4:40 Mayo Clinic’s Program for Rare and Undiagnosed Diseases (PRaUD): challenges faced and lessons learned
8:28 The Tapestry Study: integrating genomic data into patient care plans
11:40 The Tapestry Study: challenges in implementing healthcare interventions based on genetic findings
12:10 The Tapestry Study: The path to 100,000 whole exome sequences, including exciting findings, novel diagnoses, and future projections
13:20 The impact of the exposome (environmental exposures over the course of a lifetime) on genetic risk
16:45 Untapped data sources in exposome research
18:50 Linking the exposome to direct changes in cell physiology and metabolic pathways
21:34 Sources of exposome data - from blood draws to tissue samples
22:05 Painting a picture of the Center for Individualized Medicine in 20 years
23:30 Enhancing disease prevention, particularly for germline genetic diseases
26:38 Two scientists’ views on the humbling nature of biology
27:00 Mayo Clinic’s efforts to share its findings and precision medicine model with the world
28:10 Closing Remarks
179 afleveringen
MP3•Thuis aflevering
Manage episode 376935968 series 2631947
Inhoud geleverd door Sano Genetics. Alle podcastinhoud, inclusief afleveringen, afbeeldingen en podcastbeschrijvingen, wordt rechtstreeks geüpload en geleverd door Sano Genetics of hun podcastplatformpartner. Als u denkt dat iemand uw auteursrechtelijk beschermde werk zonder uw toestemming gebruikt, kunt u het hier beschreven proces https://nl.player.fm/legal volgen.
In this episode of The Genetics Podcast, we welcome Dr. Konstantinos Lazaridis, the Executive Director of the Center for Individualized Medicine at the Mayo Clinic. Tune in to learn about the impacts of genomics and individualised medicine on rare liver diseases and advanced cancers . Discover how the Mayo Clinic actively uses genomic testing, precision medicine, and environmental interventions to improve patient outcomes.
Timestamps:
0:00 Introduction
0:00 Introduction
0:32 Insights into the Center for Individualised Medicine at the Mayo Clinic, including the importance of predictive genomics, research in rare and undiagnosed diseases, and the integration of genomics into healthcare
4:40 Mayo Clinic’s Program for Rare and Undiagnosed Diseases (PRaUD): challenges faced and lessons learned
8:28 The Tapestry Study: integrating genomic data into patient care plans
11:40 The Tapestry Study: challenges in implementing healthcare interventions based on genetic findings
12:10 The Tapestry Study: The path to 100,000 whole exome sequences, including exciting findings, novel diagnoses, and future projections
13:20 The impact of the exposome (environmental exposures over the course of a lifetime) on genetic risk
16:45 Untapped data sources in exposome research
18:50 Linking the exposome to direct changes in cell physiology and metabolic pathways
21:34 Sources of exposome data - from blood draws to tissue samples
22:05 Painting a picture of the Center for Individualized Medicine in 20 years
23:30 Enhancing disease prevention, particularly for germline genetic diseases
26:38 Two scientists’ views on the humbling nature of biology
27:00 Mayo Clinic’s efforts to share its findings and precision medicine model with the world
28:10 Closing Remarks
179 afleveringen
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