CRISPR In Fungi: An Interview With Rebecca Shapiro CRISPR Cuts podcast

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Threshold

9 dagen geleden9d ago

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Threshold is a Peabody Award-winning documentary podcast about our place in the natural world. Each season, we take listeners on a journey into the heart of a complex environmental story, asking how we got here and where we might be headed. In our latest season, Hark, we hand the mic over to our planet-mates and investigate what it means to truly listen to nonhuman voices—and the cost if we don't. With mounting social and ecological crises, what happens when we tune into the life all around us? Threshold is nonprofit, listener-supported, and independently produced.

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CRISPR in Fungi: An Interview with Rebecca Shapiro

6 jaar geleden 18:07

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MP3•Thuis aflevering

Inhoud geleverd door Synthego. Alle podcastinhoud, inclusief afleveringen, afbeeldingen en podcastbeschrijvingen, wordt rechtstreeks geüpload en geleverd door Synthego of hun podcastplatformpartner. Als u denkt dat iemand uw auteursrechtelijk beschermde werk zonder uw toestemming gebruikt, kunt u het hier beschreven proces https://nl.player.fm/legal volgen.

Rebecca Shapiro, Assistant Professor at the University of Guelph, talks about CRISPR genome editing in fungal pathogens to understand their disease-causing mechanism. Her lab also works on gene drives in fungi for studying large scale genetic interactions and developing ways for treating fungal biofilms.

… continue reading

44 afleveringen

#Synthego #Biology #Science #Natural Sciences

CRISPR Cuts podcast artwork

CRISPR in Fungi: An Interview with Rebecca Shapiro

65 subscribers

published 6 jaar geleden

Delen

MP3•Thuis aflevering

Inhoud geleverd door Synthego. Alle podcastinhoud, inclusief afleveringen, afbeeldingen en podcastbeschrijvingen, wordt rechtstreeks geüpload en geleverd door Synthego of hun podcastplatformpartner. Als u denkt dat iemand uw auteursrechtelijk beschermde werk zonder uw toestemming gebruikt, kunt u het hier beschreven proces https://nl.player.fm/legal volgen.

Rebecca Shapiro, Assistant Professor at the University of Guelph, talks about CRISPR genome editing in fungal pathogens to understand their disease-causing mechanism. Her lab also works on gene drives in fungi for studying large scale genetic interactions and developing ways for treating fungal biofilms.

… continue reading

44 afleveringen

#Synthego #Biology #Science #Natural Sciences

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CRISPR Cuts

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Imran House and Junyun Lai Discuss CRISPR Screening in Immuno-Oncology 26:06

1 year geleden26:06

26:06

Imran House, Ph.D. and Junyun Lai Ph.D. are Senior Scientists at the biotech start-up, oNKo-Innate in Melbourne, Australia that focuses on developing immuno-oncology therapies. In this episode, they discussed what they do at oNKo-innate, their career transitions from leaving academics to entering the biotech industry, and how CRISPR is impacting cancer-immunotherapy development. They also discussed overcoming common obstacles faced when developing cytokine therapies and future outlooks on clinical trials using these kinds of therapies. Reach out and connect with both Imran and Junyun on social media platforms: Imran House, Ph.D. LinkedIn X: @ImranHouse Junyun Lai, Ph.D. LinkedIn X: @JunyunLai…

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Mark DeWitt and Don Kohn Discuss Their ex vivo CRISPR-based Therapy to Cure Sickle Cell Anemia 33:24

1 year geleden33:24

33:24

Dr. Mark DeWitt Ph.D., Associate Director at Mammoth Biosciences, and Dr. Don Kohn M.D., distinguished professor and Director of the UCLA Human Gene and Cell Therapy Program and CIRM grantee sat down with us to discuss their latest clinical trials to cure sickle cell anemia, how synthetic guides accelerated their journey from the bench to the clinic, and their experience in the cell and gene therapy space.…

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Dina Simkin Breaks Down Epilepsy Cell Modeling 27:24

2 years geleden27:24

27:24

Dina Simkin, Professor of Neurology at Northwestern University, joins us in this episode of CRISPR Cuts. Dr. Simkin talks about her path to becoming a researcher, art, and the importance of patient and isogenic iPSC models to study genetically linked forms of epilepsies.

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CRISPR Cuts

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Sunil Sharma and Raffaella Soldi Talk CRISPR For Unbiased Drug Screening for Rare Pediatric Cancers 24:43

2 years geleden24:43

24:43

Dr. Sunil Sharma and Dr. Raffaella Soldi of the Translational Genomics Research Institute chat about using CRISPR arrayed screens to identify novel drug targets for Ewing's Sarcoma, outlooks for the future of cancer therapies, and the Arizona heat.

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CRISPR Cuts

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Stephanie Cherqui Discusses Clinical Development of CRISPR Therapies for Rare Diseases 20:27

2 years geleden20:27

20:27

Professor Stephanie Cherqui, UCSD, has worked on the development of cell therapies for two rare genetic diseases, cystinosis and Friedreich’s ataxia. In this interview, Dr. Cherqui chats about her experience working on rare diseases, developing a CRISPR-edited therapy for Friedreich's ataxia, navigating regulatory challenges in cell and gene therapies, and more.…

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CRISPR Cuts

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Christian Groendahl On Pioneering a CRISPR-based Microbial Gene Therapy 29:11

2 years geleden29:11

29:11

Tune in to hear Christian Groendahl, CEO of SNIPR Biome, talk about CRISPR editing in prokaryotes, their novel E. coli- targeting CRISPR therapy trials, and his experiences and vision leading a start up.

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CRISPR Cuts

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Bryan Dechairo Envisions an Accessible Future for CRISPR Diagnostics 35:29

3 years geleden35:29

35:29

In this episode, Bryan Dechairo, CEO of Sherlock Biosciences, talks about the impact of technology advances in the field of CRISPR diagnostics, his experiences leading Sherlock Biosciences, and his team’s mission of accessibility.

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CRISPR Cuts

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Ayal Hendel Talks About CRISPR in Bubble Boy Disease 35:46

3 years geleden35:46

35:46

Dr. Ayal Hendel, a genome-editing pioneer and group leader at Bar Ilan University in Israel, was one of the first researchers to use modified synthetic sgRNA to edit primary cells with CRISPR. In this episode, Dr. Hendel shares his perspectives on the recent CRISPR advancements and his work on the bubble boy disease.…

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CRISPR Cuts

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Jimi Olaghere Opens up About His Sickle Cell Disease and CRISPR Trial 39:59

3 years geleden39:59

39:59

Jimi has dealt with sickle cell disease, a genetic disorder with serious implications, his entire life. Undergoing a CRISPR gene editing trial turned his hope for a cure into reality with promising results from the early phases. Tune in to learn about Jimi's journey in this episode.

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CRISPR Cuts

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TJ Cradick Speaks About Their HIV CRISPR Therapy in Trials 23:40

3 years geleden23:40

23:40

TJ Cradick, Chief Scientific Officer at Excision Bio, discusses their CRISPR HIV therapy that recently proceeded into clinical trials in this episode and their ongoing work on other viral diseases.

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CRISPR Cuts

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Bryce Olson Relays His Experience on Personalized Therapies for Cancer Patients 42:37

3 years geleden42:37

42:37

After being diagnosed with aggressive prostate cancer, Bryce Olson quickly learned the science behind it and has leveraged NGS to understand his tumor genomics and find opportunities in personalized therapies. Hear the patient perspective for the first time on our podcast through Bryce's narration of his experience and pursuit of next generation cell and gene therapies.…

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CRISPR Cuts

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Neville Sanjana Discusses Ways to Enhance CRISPR-Cas13 Knockdown in Human Cells 32:52

3 years geleden32:52

32:52

In this collaboration episode with NEB, we interview Dr. Neville Sanjana, a core faculty member at the New York Genome Center, about his recent publication in which chemically modified guide RNAs were used to enhance CRISPR-Cas13 knockdown in human cells.

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CRISPR Cuts

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Kiana Aran Chats About her Nature Award and New Non-Profit 41:09

3 years geleden41:09

41:09

In this episode, we chat with Dr. Kiana Aran, the CSO of Cardea Bio and associate professor at Keck Graduate Institute, who recently won the Nature Research Award for Inspiring Women in Science. Dr. Aran talks about her experience being a nominee and award winner, her early days and scientific journey, and the launch of her new non-profit, Aran Nebula.…

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CRISPR Cuts

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6 Women CRISPR Leaders Get Candid About Their Journeys to the Top 1:02:44

3 years geleden1:02:44

1:02:44

We chatted with six female leaders in the CRISPR—Alison van Eenennaam, Ph.D., Kiana Aran, Christina Trojel-Hansen, Ph.D., Laura Lambert, Ph.D., Elena Miñones Moyano, Ph.D., and Samantha Maragh, Ph.D.— about their professional journeys. Tune in to this episode for a candid and honest discussion on a broad range of topics, including their experiences as women of color, life as working moms, adjusting in male-dominated fields, experiences being part of the LGBTQIA community, and the role of mentors in professional development.…

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CRISPR Cuts

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Jesse Boehm Discusses Tackling Rare Cancers Using CRISPR 30:35

4 years geleden30:35

30:35

In this CRISPR Cuts episode, Dr. Jesse Boehm, the Chief Scientific Officer of the Break Through Cancer Foundation and principal investigator at the Broad Institute, talks about his work on rare cancers. He also covers how CRISPR technology is transforming cancer research.

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