In Vitro Bioaccessibility Assay (IVBA) Sampling Guidance Update - Part 1 (Feb 12, 2024)

Contaminated Site Clean-Up Information (CLU-IN): Internet Seminar Video Archives

The Technical Review Workgroup (TRW) Bioavailability Committee recently published the "Guidance for Sample Collection for In Vitro Bioaccessibility Assay for Arsenic and Lead in Soil and Applications of Relative Bioavailability Data in Human Health Risk Assessment." This is an update to the 2015 Guidance for Sample Collection for In Vitro Bioaccessibility Assay for Lead (Pb) in Soil. The update is intended to help EPA risk assessors, remedial project managers, and on-scene coordinators develop and use bioavailability data at their sites. It incorporates sample planning and data analysis recommendations from EPA's Guidance on Systematic Planning Using the Data Quality Objectives Process that are pertinent to sampling for In Vitro Bioaccessibility (IVBA) and Relative Bioavailability (RBA). It also clarifies the application of IVBA and RBA data to human health risk assessment, the development of risk-based goals at CERCLA remedial and removal sites and includes arsenic (As) which was recently added to the In Vitro Bioaccessibility Assay. The TRW has developed a series of trainings based on the updated guidance. This first session will cover what bioavailability is and why we should measure it for Pb and As at Superfund removal and remedial sites, as well as for other cleanup programs. This training will target a general audience of regional staff working in risk assessment, remediation, emergency response, technical support, and quality assurance. The training will be an hour long and will include plenty of time for general discussion. Members of the Bioavailability Committee and a Regional representative will be present to answer questions in real time. To view this archive online or download the slides associated with this seminar, please visit http://www.clu-in.org/conf/tio/IVBA_021224/