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In this podcast series, editors-in-chief from the JACC family of specialty journals provide highlights and summarize key findings for select issues. Published by the American College of Cardiology, the JACC Journals publish peer-reviewed articles on all aspects of cardiovascular disease, including original clinical studies, translational investigations with clear clinical relevance, state-of-the art papers, and review articles. They are top ranked for impact factor and their manuscripts are ...
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Each week, Valentin Fuster, MD, PhD, MACC, records free podcasts highlighting journal findings. To keep clinicians updated on the most important science emerging in clinical and translational cardiology, Dr. Fuster provides an overview of the weekly edition from the Journal of the American College of Cardiology (JACC), as well as a short summary of each manuscript. Encompassing JACC and nine cardiovascular specialty journals, the JACC family of journals rank among the top cardiovascular peer ...
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This occasional series from the American College of Cardiology, developed by members for members, features conversational expert interviews on non-clinical competencies, skills, well-being, and best practices for the entire heart care team.
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The CardioOhio podcast brings you fascinating interviews with local cardiovascular experts, with the goal of providing practical insights on timely topics in cardiology. It is a production of the Ohio Chapter of the American College of Cardiology. Our mission is to serve as the professional home for cardiovascular team members and to optimize cardiovascular health in Ohio.
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Drug-Coated Balloon Angioplasty Of the Side Branch During Provisional Stenting: The Multicenter Randomized DCB-BIF Trial
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Author Shao-Liang Chen, MD, FACC, and JACC Associate Editor Celina M. Yong, MD, FACC, discuss patients with simple and true coronary bifurcation lesions undergoing provisional stenting. Main vessel stenting with a DCB for the compromised side branch resulted in a lower 1-year rate of the composite outcome compared with an NCB intervention for the s…
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Transcatheter Aortic Valve Replacement in Patients With Systolic Heart Failure and Moderate Aortic Stenosis: TAVR UNLOAD
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Author Nicolas M. Van Mieghem, MD, PhD, FACC, and JACC: Executive Associate Editor Aakriti Gupta, MD, FACC, discuss the TAVR UNLOAD trial, which focused on patients with moderate aortic stenosis (AS) and reduced ejection fraction (HFrEF). The trial found no significant difference in the primary endpoint (composite of mortality, stroke, and hospital…
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Family Screening in Hypertrophic Cardiomyopathy - Identification of Relatives with Low Yield from Systematic Follow-up
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In this episode, Dr. Valentin Fuster dives into a pivotal study on hypertrophic cardiomyopathy, focusing on the challenges of identifying at-risk relatives when genetic variants are not found in 60% of families. With insights into the disease's autosomal dominant inheritance and incomplete penetrance, this discussion highlights the complexities of …
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Impact of Aficamten on Echocardiographic Cardiac Structure and Function in Symptomatic Obstructive Hypertrophic Cardiomyopathy
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In this episode, Dr. Valentin Fuster delves into a groundbreaking study on the effects of the cardiac myosin inhibitor, Aficamten, on patients with obstructive hypertrophic cardiomyopathy. The findings reveal significant improvements in echocardiographic measures of cardiac function, despite a mild and reversible decrease in left ventricular ejecti…
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JACC - November 5, 2024 Issue Summary
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In the November 5, 2024 issue of JACC, Dr. Valentin Fuster summarizes the November 5, 2024 issue of the JACC, which focuses exclusively on hypertrophic cardiomyopathy (HCM). Highlighting six original research papers, the discussion emphasizes the groundbreaking impact of the cardiac myosin inhibitor Aficamten on health outcomes, symptom burden, and…
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Effect of Aficamten on Health Status Outcomes in Obstructive Hypertrophic Cardiomyopathy: Results from SEQUOIA-HCM
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In this episode, Dr. Valentin Fuster delves into the latest research on hypertrophic cardiomyopathy, highlighting the significant health status improvements achieved with the new cardiac myosin inhibitor, Aficamten, compared to placebo. The findings from the Sequoia HCM study reveal that Aficamten markedly enhances patients' quality of life and all…
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Effect of Aficamten on Cardiac Structure and Function in Obstructive Hypertrophic Cardiomyopathy: SEQUOIA-HCM CMR Substudy
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In this episode, Dr. Valentin Fuster explores groundbreaking research on hypertrophic cardiomyopathy, focusing on the effects of the drug aficamten on cardiac structure and function. Highlighting significant findings from the Sequoia HCM trial, the discussion underscores the potential of aficamten to induce favorable cardiac remodeling and improve …
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Standard of Care Medication Withdrawal in Patients With Obstructive Hypertrophic Cardiomyopathy Receiving Aficamten in FOREST-HCM
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In this episode, Dr. Valentin Fuster highlights the Forest HCM study, which focuses on the withdrawal of standard care medications in patients with obstructive hypertrophic cardiomyopathy receiving afficantin. The study shows promising results: nearly half of the patients who attempted to reduce or stop their medications did so successfully, with s…
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Impact of Aficamten on Disease and Symptom Burden in Obstructive Hypertrophic Cardiomyopathy: Results from SEQUOIA-HCM
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In this episode, Dr. Valentin Fuster introduces a dedicated focus on hypertrophic cardiomyopathy, featuring a pivotal study by Dr. Martin Maron and Dr. lacopo Olivotto on the impact of aficamptin. This pre-specified sub-analysis from the SEQUOIA HCM trial aims to comprehensively evaluate the drug's effects on various aspects of disease burden, enha…
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Transcatheter Valve Repair for Tricuspid Regurgitation: 1-Year Results From a Large European Real-World Registry
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Author Joerg Hausleiter, MD and Executive Associate Editor Aakriti Gupta, MD, FACC. discuss the TAVR UNLOAD trial, which focused on patients with moderate aortic stenosis (AS) and reduced ejection fraction (HFrEF). The trial found no significant difference in the primary endpoint (composite of mortality, stroke, and hospitalizations) between the TA…
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Tricuspid Transcatheter Edge-to-Edge Repair for Severe Tricuspid Regurgitation: 1-year Outcomes From the TRILUMINATE Randomized Cohort
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JACC Associate Editor Celina M. Yong, MD, FACC, and JACC: Case Reports Editor in Chief Gilbert H. L. Tang, MD, MSc, MBA, FACC, discuss this paper published in JACC and presented at TCT. TRILUMINATE Pivotal is the first randomized, controlled trial evaluating transcatheter edge-to-edge repair (T-TEER) for severe tricuspid regurgitation (TR). Adaptiv…
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JACC: Cardiovascular Interventions - IVUS-Guided vs Angiography-Guided PCI in Patients With Diabetes With Acute Coronary Syndromes: The IVUS-ACS Trial
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In this episode, Dr. Abdullah Al-Abcha and Dr. Shao-Liang Chen, discusses the groundbreaking findings of the Ivis ACS trial, which compares Ivis-guided versus angiography-guided PCI in diabetic patients with acute coronary syndrome. The results reveal a significant reduction in target vessel failure for Ivis-guided procedures, underscoring the need…
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JACC: Cardiovascular Interventions - Association of Physician Certification and Outcomes Among Patients Undergoing Left Atrial Appendage Occlusion
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Abdullah Al-Abcha, MD, social media editor of JACC: Cardiovascular Interventions, and Amit N. Vora, MD, MPH, FACC, discuss a recently published original research paper reporting the association of physician certification and outcomes among patients undergoing left atrial appendage occlusion.
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JACC: Advances - Lipoprotein(a) Levels in Severe Aortic Stenosis Referred for Transcatheter Aortic Valve Implantation Compared to Controls
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Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on lipoprotein(a) levels in severe aortic stenosis referred for transcatheter aortic valve implantation compared to controls.
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JACC Edge Podcast - Innovations in Interventional Cardiology: Frightfully Delightful!
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In this episode of the JACC Edge podcast, hosts Pratik Doshi and Dr. Manesh Patel explore the frontiers of interventional cardiology, emphasizing the crucial role of innovation and digital tools like AI in improving patient outcomes. Dr. Patel shares insights on the importance of bridging clinical practice and research, as well as fostering communi…
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JACC: Advances - Coronary Artery Calcium for Risk Stratification Among Persons With Very High HDL Cholesterol
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Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on coronary artery calcium for risk stratification among persons with very high HDL cholesterol.
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JACC: Clinical Electrophysiology - Clinical Characteristics and Outcomes in Patients with Atrial Fibrillation and Pathogenic TTN Variants
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Emile Daoud, MD, Associate Editor of JACC: Clinical Electrophysiology discusses a recently published original research paper on Clinical Characteristics and Outcomes in Patients with Atrial Fibrillation and Pathogenic TTN Variants.
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JACC: Advances - Long-Term Outcomes of Patients With Apical Hypertrophic Cardiomyopathy Utilizing a New Risk Score
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Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on long-term outcomes of patients with apical hypertrophic cardiomyopathy utilizing a new risk score.
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Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on mortality burden for patients with untreated aortic regurgitation.
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JACC: Advances - Clinical Course and Treatment of Patients With Apical Aneurysms Due to Hypertrophic Cardiomyopathy
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Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances discusses a recently published original research paper on clinical course and treatment of patients with apical aneurysms due to hypertrophic cardiomyopathy.
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JACC: Advances - A Novel Echocardiographic Parameter to Confirm Low-Gradient Aortic Stenosis Severity
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Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper about a novel echocardiographic parameter to confirm low-gradient aortic stenosis severity.
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JACC: Advances - Left Ventricular Wall Stress and Incident Heart Failure in Elderly Community-Dwelling Individuals
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Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on left ventricular wall stress and incident heart failure in elderly community-dwelling individuals.
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JACC: Advances - AI-Derived Left Ventricular Mass From Noncontrast Cardiac CT: Correlation With Contrast CT Angiography and CMR
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Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on AI-derived left ventricular mass from noncontrast cardiac CT including a correlation with contrast CT angiography and CMR.
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JACC: Advances - Sex-Related Differences in Left Ventricular Geometry Patterns in Patients With Arterial Hypertension
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Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on sex-related differences in left ventricular geometry patterns in patients with arterial hypertension.
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