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Gordan Lauc PhD: Glycans- The Next Biological Longevity Clock?

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Manage episode 302876619 series 2981357
Inhoud geleverd door Robert Lufkin MD. Alle podcastinhoud, inclusief afleveringen, afbeeldingen en podcastbeschrijvingen, wordt rechtstreeks geüpload en geleverd door Robert Lufkin MD of hun podcastplatformpartner. Als u denkt dat iemand uw auteursrechtelijk beschermde werk zonder uw toestemming gebruikt, kunt u het hier beschreven proces https://nl.player.fm/legal volgen.

#011-Glycans are being hailed as possibly the next great biological longevity clock. Today we speak with the leading expert on the subject.
Gordan Lauc PhD, is Professor of Biochemistry and Molecular biology at the University of Zagreb and Co-Founder and Chief Scientific Officer at GlycanAge. He graduated from the University of Zagreb Faculty of Science in 1992, and obtained PhD in Biochemistry and the University of Zagreb.

Take home points:

Glycans– the third revolution in evolution

Nuclei acids - 4 building blocks [linear]
Proteins - 20 amino acids [linear]
Glycoproteins- 2000+ [nonlinear]

Examples -Blood groups ABO are glycans

Post translational-make protein

Glycans modifications of proteins lipids and even DNA by sugar

Nonlinear branching oligosaccharide

Glucose-monosaccharide-

Post translational modifications-

Phosphorylation

Glycosylation

AGE- advanced glycation end products——reaction glucose and proteins- not the same as glycosylation.

Immunoglobulins- older get more pro inflammatory glycans-

Igg glycosylation suppress inflammation

Human glycan project

Health Longevity Secrets show listeners who wish to try The Glyconage longevity clock on themselves can receive a 20% discount enter the code ROBERTLUFKIN at the glycanage.com website.

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NOTE: This is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have. Never disregard professional medical advice or delay in seeking it because of something you have seen here. Robert Lufkin MD may at any time and at its sole discretion change or replace the information available on

*** CONNECT WITH ROB ON SOCIAL MEDIA ( 300k++)***

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Threads:
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*** SPONSORSHIPS & BRANDS ***
We do work with sponsors and brands. If you are interested in working with us for your health industry product or service, please contact us at: https://www.robertlufkinmd.com/contact/
NOTE:
This is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have. Never disregard professional medical advice or delay in seeking it becaus...

  continue reading

147 afleveringen

Artwork
iconDelen
 
Manage episode 302876619 series 2981357
Inhoud geleverd door Robert Lufkin MD. Alle podcastinhoud, inclusief afleveringen, afbeeldingen en podcastbeschrijvingen, wordt rechtstreeks geüpload en geleverd door Robert Lufkin MD of hun podcastplatformpartner. Als u denkt dat iemand uw auteursrechtelijk beschermde werk zonder uw toestemming gebruikt, kunt u het hier beschreven proces https://nl.player.fm/legal volgen.

#011-Glycans are being hailed as possibly the next great biological longevity clock. Today we speak with the leading expert on the subject.
Gordan Lauc PhD, is Professor of Biochemistry and Molecular biology at the University of Zagreb and Co-Founder and Chief Scientific Officer at GlycanAge. He graduated from the University of Zagreb Faculty of Science in 1992, and obtained PhD in Biochemistry and the University of Zagreb.

Take home points:

Glycans– the third revolution in evolution

Nuclei acids - 4 building blocks [linear]
Proteins - 20 amino acids [linear]
Glycoproteins- 2000+ [nonlinear]

Examples -Blood groups ABO are glycans

Post translational-make protein

Glycans modifications of proteins lipids and even DNA by sugar

Nonlinear branching oligosaccharide

Glucose-monosaccharide-

Post translational modifications-

Phosphorylation

Glycosylation

AGE- advanced glycation end products——reaction glucose and proteins- not the same as glycosylation.

Immunoglobulins- older get more pro inflammatory glycans-

Igg glycosylation suppress inflammation

Human glycan project

Health Longevity Secrets show listeners who wish to try The Glyconage longevity clock on themselves can receive a 20% discount enter the code ROBERTLUFKIN at the glycanage.com website.

*** SUBSCRIBE TO ROBERT LUFKIN MD YOUTUBE CHANNEL HERE *** https://www.youtube.com/channel/UC2w2...

*** CONNECT WITH ROBERT LUFKIN MD ON SOCIAL MEDIA ***

Web: https://robertlufkinmd.com/

Twitter:https://twitter.com/robertlufkinmd

*** GOT A SUGGESTION FOR A SHOW? ***

Contact us at: https://robertlufkinmd.com/contact

*** SPONSORSHIPS & BRANDS ***
We do work with sponsors and brands. If you are interested in working with us and you have a product or service that is of value to the health industry please contact us at: https://robertlufkinmd.com/contact​

NOTE: This is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have. Never disregard professional medical advice or delay in seeking it because of something you have seen here. Robert Lufkin MD may at any time and at its sole discretion change or replace the information available on

*** CONNECT WITH ROB ON SOCIAL MEDIA ( 300k++)***

Web: https://robertlufkinmd.com/
X:
https://x.com/robertlufkinmd
Youtube:
https://www.youtube.com/RobertLufkinMD
Instagram:
https://www.instagram.com/robertlufkinmd/
LinkedIn:
https://www.linkedin.com/in/robertlufkinmd/
Facebook:
https://www.facebook.com/robertlufkinmd
Threads:
https://www.threads.net/@robertlufkinmd

*** SPONSORSHIPS & BRANDS ***
We do work with sponsors and brands. If you are interested in working with us for your health industry product or service, please contact us at: https://www.robertlufkinmd.com/contact/
NOTE:
This is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have. Never disregard professional medical advice or delay in seeking it becaus...

  continue reading

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