Our podcasts are geared towards listeners who desire knowledge regarding fundamental truths and wisdom. Though our content varies from series to series, the presentations are always based on evidence. As the 21st century unfolds and the entire world wakes up every day to a fog of media-supported illusions, our content is designed to counteract these insidious forces.
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Profane, insane, and 100% primo science, Petri Dish is a no-BS podcast that explores the wildest subjects in modern science with clarity and evil joy. Hosted by Sean Allen, a Nanoparticle/Immunology Researcher, and Nathan Allen, his "screenwriter" brother, Petri Dish fuses hard science with a freewheeling and madcap conversational style. Cannabinoids, Plague, Cats, the dreaded Candiru, and the even more dreaded Covid-19: all these and more are dissected with intellect and irreverence, droppi ...
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Part 1 - 21 Fundamental Truths - Analyzing the 2024 Election
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Jim analyzes the 2024 election within the context of 21 Fundamental Truths, particularly the human tendencies associated with Hatred and Group Identity. Of particularly interest is the evaluation of the the finite mathematical limits associated with gender and political strategies based on dividing the general population based on group identity.…
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Part 3 Artificial Intelligence – The Dawn of a 2nd Industrial Revolution - A Rational Perspective on Investments
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Jim addresses seven key questions in his detailed look at Generative Artificial Intelligence. 1. What are the most relevant points in the history of modern computing? 2. What are the basic facts associated with Generative A.I. that must be understood for a more rational perspective on investments. 3. What will be the impact of A.I. on the global co…
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Part 2 Properly Framing the Digital Age and the Industrial Revolution - A Rational Perspective on Investments
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Jim uses the common threads of the 1) demand for SPEED and 2) demand for ever-improving methods of information gathering and analysis into historical perspective in this segment to help listeners prepare themselves for the best ways to think about Generative Artificial Intelligence, which is the topic of Part 3, the series finale.…
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Part 1 Understanding the Nature of Change and Its Impact on Investments - A Rational Perspective on Investments
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Jim addresses the nature of change in this segment as he begins the process of preparing listeners to understand the best way to think about the current environment for investments.Door Petri Dish Foundation
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Part 11 - Students, Apprentices, and Disciples
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Part 11 makes extensive use of Dallas Willard’s book, The Divine Conspiracy, in this segment Jim connects the dots on the previous ten segments. The implications of layer after layer of sweeping evidence are discussed in terms of what should be done by individuals seeking Answers to the Great Question. Observations on Consumer Christians are examin…
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Part 10 - The Great Transition
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Part 10 begins with the recognition of a phrase coined by the late great Dr. Dallas Willard of the University of Southern California. According to Dr. Willard, "The Great Transition," is the period one enters immediately after one recognizes he or she has the freedom to choose their own teacher. The stunning contrasts between the teachings of Machi…
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Part 9 - Higher Education’s Sports Marketing and Entertainment Businesses
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Part 9 provides more powerful evidence supporting the troubling theme of the entire series. In this segment, the number of higher education perpetrators expands geometrically. The segment begins with an examination of an announcement by the NCAA, of an astonishing $2.8 billion settlement offer made in May of 2024 to compensate more than 14,000 stud…
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Part 8 - Who is your teacher?
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Part 8 puts Harvard University under the integrity microscope. Eyewitnesses in this segment include Derek Bok who served as president of Harvard University for 20 years (1971 – 1991) and faculty member Dr. Robert Coles who was awarded the Presidential Medal of Freedom by President Clinton in 1998. This segment provides chilling details of how the h…
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Part 7 - Distinguishing Between Teachers and Educational Institutions
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Part 7 explores the overwhelming evidence that distinguishes teachers from educational institutions. The patterns of “mission abandonment” by institutions controlling education systems throughout human history are laid bare, including the fundamental tendency of ruling bureaucracies to selectively obscure the findings of mankind’s greatest scientis…
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Part 6 - Pain, Suffering, and Self-Appointed Gatekeepers of the Truth
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Part 6 answers an important student question and also employs basic logic to expose the inherent dangers of “OUTSOURCING” fact-finding processes to scandal-plagued bureaucracies in efforts to Answer the Great Question. Given the obvious abandonment of primary missions by self-appointed, “gatekeepers of the truth,” the film encourages independent cr…
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Part 5 - Why Mathematics Matter
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Part 5 illustrates how mathematics is being selectively applied as if it were a retractable tool. Only some mathematical illustrations are useful to ruling bureaucracies. And layer after layer of evidence suggests that contradictory mathematical realities are frequently withheld from presentations of implausible theories that bureaucracies want to …
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Part 4 - The Theological Evidence
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Part 4 shifts gears with thorough attention paid to theological evidence trails. Part 4 includes an abundance of relevant facts from controlled studies by behavioral scientists that are entirely relevant, due to their direct connections to efforts to Answer the Great Question.Door Petri Dish Foundation
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Part 3 - Quantum Entanglement - Some Spirit
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Part 3 explores the sweeping implications to Answering the Great Question with the 2022 Nobel Prize in Physics award for work on Quantum Entanglement. Revealing statements by the Nobel Committee itself of the presence of “philosophical issues” are thoroughly dissected.Door Petri Dish Foundation
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Part 2 - Publish or Perish Scandals Erupt in 2023
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Part 2 examines the eruption of academic scandals over the last two decades including more than 10,000 retractions of “peer reviewed” scientific papers by scientific journals in 2023 alone. This amounts to more than 27 papers per day, 365 days a year being published as valid “science,” only to be withdrawn after independent investigations by third …
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Part 1 - A Bad Five Act Play
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Part 1 of the series begins with a little-know statement made by Albert Einstein in 1936. It was discovered in a private letter found in his personal papers after his death. Einstein’s conclusions have been buried outside of the view of students for 70 years. The opening segment traces a litany of inappropriate practices employed by ruling educatio…
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Ep. 185 How to Make a Drug Pt 2: Libraries and Design
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On this second episode about drug discovery, we discuss small molecule drug libraries and the challenges behind rational design! Don't know what that means? Tune in to find out! References: https://www.frontiersin.org/articles/10.3389/fcell.2019.00107/full https://next.cancer.gov/discoveryresources/resources_ndl.htm https://www.molbiolcell.org/doi/…
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Ep. 184 How to Make a Drug Pt 1: A Target
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Hey everyone! Today's episode is about getting into the nitty gritty of drug discovery. We often benefit from the research and development that goes into the creation of drugs we use to treat illnesses without really understanding what goes into that process. In this first part, we will discuss how you conceptually begin the process. References: ht…
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Ep. 183 Influenza Pt 4: Vaccines and Pandemics
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Sorry for the COVID-related break in episodes everyone! In our return, we complete our series on influenza by discussing past epidemics and pandemics to understand how influenza has repeatedly led to large scale medical events. Then we will finish by discussing the current and future state of influenza vaccines! References: https://www.nejm.org/doi…
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Ep. 182 Influenza Pt 3: Whaddya Gonna Do About It?
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You've had the flu. You've had a cold. Maybe you've even had allergies! But how can you tell them apart? And if you even figure out that you do have influenza, are there any treatments you can take that can help? References: https://www.health.harvard.edu/staying-healthy/gastroenteritis-in-adults-a-to-z https://academic.oup.com/aje/article/182/4/29…
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Ep. 181 Influenza Pt 2: The Piggies
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Last episode we discussed the current H5N1 flu that is hitting birds pretty hard. But is bird flu different from swine flu? Is there just a 'human flu', or do we only catch influenza from other animals? Let's get into the evolutionary history of the flu and primary hosts! References: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328453/ https://www…
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Ep. 180 Influenza Pt 1: Highly Pathogenic Avian Influenza
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Today's episode is the first in a four-part series on influenza! This time we are covering just enough background information to discuss the recent H5N1 pandemic in birds, which was responsible for the egg shortage and has been killing a lot of wild birds. References: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074182/ https://www.ncbi.nlm.nih.go…
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Ep. 179 The Silence of the Plants
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Sure, plants can sometimes smell good and they do cool stuff like make carbs for us to eat and oxygen for us to breathe. But they sort of look like they're just passively sitting there, right? Just chilling. If only we could hear just a slightly broader range of frequencies, we would hear a whole new world of plants -- one where they are complainin…
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Ep. 178 A Baby Born of Two Daddies
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Hi everyone! This week's episode is about recent work trying to figure out a way to make a baby mouse that has two genetic dads. We also dive into why mammals don't seem to have virgin births!References: https://www.nature.com/articles/cr201115 https://pubmed.ncbi.nlm.nih.gov/17034046/ https://www.nature.com/articles/nature02402 https://www.nature.…
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Ep. 177 Black Holes Pt 2: Quasi-Stars and Quasars
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Today's episode is our second and final episode on Black Holes! We cover some exotic black hole concepts, like whether they are a source of dark energy, what a white hole is, and whether black holes are fuzzy or not! References: https://www.science.org/content/article/dark-energy-supermassive-black-holes-physicists-spar-over-radical-idea https://sc…
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Ep. 176 Black Holes Pt 1: Curvy Thicc Spacetime Stuff
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Here in our first episode on our 2-parter on Black Holes, we explain what a black hole is in theory and what it probably actually is in practice. We dive into why it is still hard for us to really know what the true nature of black holes are and we discuss the different kinds of black holes.References: https://forums.space.com/threads/how-to-calcul…
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Ep. 175 The Norfolk Southern Environmental Trainwreck
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In February, a train was partially derailed while carrying a number of chemicals. The subsequent attempt at containment resulted in the release of many thousands of gallons of these chemicals. What were those chemicals? What are the risks involved in their release? References: https://www.nytimes.com/article/ohio-train-derailment.html https://www.n…
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Ep. 174 Desalination Pt 2: A Not-So-Salty Future?
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On this week's episode, we complete our series on desalination by discussing the near future technologies that are coming to either improve or attempt to supplant the current front runners that we discussed last week. We will also discuss the downsides of desalination and work that is being done to try to minimize or circumvent them! References: ht…
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Last of Us Rerelease! Fungus Pt 2: Cordyceps and More!
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Hi Everyone! We're interrupting our series on desalination to put out a quick rerelease of one of our episodes on Fungi! We're doing this in honor of the season 1 finale of The Last of Us, which heavily features a fungus called Cordyceps, which we covered in this episode. Check it out and learn more about cordyceps, similar fungi, and much nicer fu…
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Ep. 173 Desalination Pt 1: So Salty
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Climate change is happening, two billion people don't have a reliable and safe supply of fresh water, and the problem isn't likely to get a whole lot better on its own! Desalination is the process of making fresh water from salt water, but what is the current state of the technology? Find out on this episode of Petri Dish! Next time, we will discus…
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Ep. 172 VEXAS: A Mystery Syndrome
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While science and medicine have come a long way over the centuries, there are still illnesses that cannot be explained -- and many of them are autoinflammatory disorders. Many people all over the world have been inflicted with these disorders with no clear cause. But recently, scientists were able to find a mutation that can help explain what some …
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Ep. 171 Side Quests 2: Cancer and Concrete
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Occasionally we do episodes where we speak about a couple different topics that don't have a specific underlying theme -- they're just fun science papers that have cropped up recently! This time we discuss the confluence of two different hot technologies, CRISPR base editing and CAR T cells. We also do a little dive into Roman Concrete! References:…
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Ep. 170 Death Pt 2: A Twitching Heart
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We return with our second episode on Death, the final frontier! What is it? Actually though, like what determines the moment when someone dies? This question has actually had a different answer through the years, and we dive into the definition and how it has changed as technology has advanced. We finish with an example of cutting-edge technology t…
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Ep 169 Death Pt.1: Disembodied Pig Brains
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On our first episode about Death, we look into a paper published a few years that described the reanimation of a pig brain! Spooky! Let’s get into the science behind it and some of its implications for humans!
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This winter season the world is dealing with not two but three respiratory illnesses at the same time. While these are familiar names at this point, they’re definitely different from one another, so let’s get into COVID, the flu, and RSV!
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Ep. 167 Coffee Pt 2: Dry, Wet, Honey, and Poop
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Hi Folks! Part 2 of our series on coffee focuses on how coffee beans can be imparted with different flavors through their picking and processing! We mentioned this in the show notes for the last episode, but we will be going on a couple month hiatus while Nathan and Stacey take a vacation in Korea! We will be re-releasing some of our older episodes…
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Ep. 166 Coffee Pt 1: Species and History
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The first episode on our three part series is on the history of human consumption of coffee (as far as we know) and the several species of plant that can produce those sweet, sweet beans! As a note, we are going to be taking a hiatus after Pt 2 next week for Nathan and Stacey to take a well-earned break and enjoy some time in Korea! We are going to…
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Ep. 165 Viral Hepatitis Pt 2: The Chronic
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In our second and final episode on viral hepatitis, we discuss Hepatitis B and Hepatitis C! One has a vaccine, the other can be treated with antivirals, but both can be pretty serious and bad if you aren't protected or treated. Our sponsor is Athletic Greens, a really solid and easy way to get your vitamins if you're like me and are too silly/busy …
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Ep. 164 Viral Hepatitis Pt 1: Acute But Not Cute
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In our first episode of a two parter, we discuss what the liver does, what hepatitis is generally, and which hepatitis viruses cause acute issues! References: https://link.springer.com/article/10.1007/s00705-022-05375-0 https://www.ncbi.nlm.nih.gov/books/NBK13296/ https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0227670 https://www…
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Ep. 163 Random Walks, Brownian Motion, and the Physics of Big Bacteria
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Last week, we discussed a very big bacterium, one you can see with your naked eye! But back in high school we all learned that bacteria and prokaryotes in general were pretty simple cells and were definitely smaller than our cells. While we've found a lot of examples that push back against this idea, there is a fundamental truth behind it -- a simp…
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Ep. 162 Really Huge Bacteria
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In today's episode, we discuss a recent discovery of a reaaaaaally big bacteria, like way big! Big enough that you can see it without a microscope! Longer than a fruit fly! BIG! How can a bacteria get so big? What is going on there? Let's discuss it! References: https://www.science.org/doi/10.1126/science.abb3634 https://www.science.org/content/art…
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Ep. 161 Monkeypox Pt 2: APOBEC3 and Microevolution
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Sorry about the delay in this release folks! In this episode, we revisit the current unusual Monkeypox outbreak and dive into the DNA of this virus to try to understand why it is so much more global this time. Spoiler alert: the DNA currently doesn't have answers for us, but it seems to be mutating faster than normal! References: https://www.cdc.go…
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Ep. 160 Caffeine Pt 2: Muscles and Sensitivity
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In the second and final episode on our series on Caffeine, we dive into what acute caffeine toxicity can look like, along with other ways people can be sensitive to caffeine. We also discuss whether caffeine can be useful for giving you a boost while exercising! Our sponsor is Athletic Greens, a really solid and easy way to get your vitamins if you…
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Ep. 159 Caffeine Pt 1: The Most Popular Psychoactive Drug in the World
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First episode of our two-parter on caffeine! For such a small and unassuming molecule, this drug is really popular, consumed all over the world for millennia! What is caffeine? How does it work? We'll even begin to discuss why some people are more sensitive to caffeine than other people. References: https://coffeeaffection.com/coffee-cherry/ https:…
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Ep. 158 Alzheimer's Redux: Lies, Fraud, and Misconduct
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The world of Alzheimer's research has recently been rocked by very strong evidence of scientific misconduct and fraud, specifically relating to a historically relevant paper about amyloid beta oligomers as a potential cause of Alzheimer's Disease. There are a lot of nuances and complexities at play here, which we dive into! There are also some... n…
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Hi folks! I know most people don't really want to hear it, but we have another disease running around the world besides COVID and the more you know the facts, the better you can do what you can to avoid it! Learn about monkeypox on this week's episode of Petri Dish! References: https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON390 …
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Ep. 156 Venom Pt 3: Medicine and Mammals
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The final episode in our series on venom, we discuss how venom can be used in modern medicine before discussing some venomous reptiles. Then we finish up by talking about the very few and very strange venomous mammals! References: https://www.frontiersin.org/articles/10.3389/fevo.2019.00218/full https://www.accessdata.fda.gov/drugsatfda_docs/label/…
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Ep. 155 Venom Pt 2: Animal Extravaganza
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Part two of our series on venom! We start out talking about some venomous jellyfish and other cnidarians before moving on to arthropods, like some very venomous spiders! Then we go into treatment options for venom before finishing with some very strange venomous amphibians! Not just poisonous! Venomous! Our sponsor is Athletic Greens, a really soli…
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Ep. 154 Venom Pt 1: Bites and Stings and Ouchie Things
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Hi Everyone! Welcome to the first episode of our series on venom! We previously discussed toxic stuff, and venoms are a specific subset of toxic things that are introduced to the body by bite or injection rather than getting swallowed or inhaled or whatever. In this first episode we give a breakdown of the different kinds of venom, and in the follo…
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Ep. 153 Hot Dogs and Nitrates
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Happy 4th of July to all our listeners in the USA! In honor of the holiday, we're doing an episode on hot dogs and other cured meats, specifically regarding the health impacts of nitrates/nitrites! Our sponsor is Athletic Greens, a really solid and easy way to get your vitamins if you're like me and are too silly/busy to cook proper meals every day…
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Ep. 152 Doping Pt 2: Up For Debate
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In our first episode on the topic, we introduced the idea and definition of doping. In this episode we dive into blood doping, gene and cell doping, and a little debate about whether doping really is all that bad. References: https://www.wada-ama.org/en/prohibited-list https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547746/ https://pubmed.ncbi.nlm.ni…
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