Beste Bolus Education Delivered Stat podcasts (2024)

1
S05E10 Transforming End Of Life Care with Gehan Soosaipillai, Lina Pereira And Will Townsend 22:46

3+ y ago22:46

22:46

Gehan Soosaipillai and Lina Pereira are members of the Transforming End of Life Care team, and have been embedded within the Lymphoma team at UCLH for the last 12 months. Will Townsend is a Lymphoma consultant and joins us for his third Bolus episode today. We focus on the topic of 'how can End of Life care be improved'? We discuss Advanced and Par…

1
S05E09 Chronic Graft Versus Host Disease With Ronjon Chakraverty 19:46

3+ y ago19:46

19:46

Following on from his episode on Acute Graft Versus Host Disease (GVHD), Ronjon Chakraverty returns to tackle Chronic GVHD.Door Sonia Thomas, Sarah Jordan and Gavin Cooper

1
S05E08 Antimicrobial Resistance With Vanya Gant 16:56

3+ y ago16:56

16:56

We are again joined by UCLH Consultant Microbiologist Vanya Gant, for a sobering discussion on the increasing difficulty antimicrobial resistance (AMR) is causing in healthcare. As the era of effective antibiotics fades, we discuss the causes and potential ways forward. We look at how phages and plasmids can spread AMR traits across the bacterial e…

1
S05E07 Haemophagocytic Lymphohistiocytosis (HLH) With Jessica Manson 26:12

3+ y ago26:12

26:12

Haemophagocytic Lymphohistiocytosis is being diagnosed ever more as it becomes more widely known and better understood. We ask UCLH Consultant Rheumatologist Jessica Manson to give us some insight into Primary and Secondary HLH, including the various diseases that can precipitate a Secondary case, such as rheumatology conditions, lymphoproliferativ…

1
S05E06 Lung Complications In Haematology Patients With Jeremy Brown 23:32

3+ y ago23:32

23:32

Jeremy Brown is a Respiratory Consultant at UCLH, with an interest in the lung complications patients experience following chemotherapy and stem cell transplantation. We discuss the issues caused by Bacterial Pneumonia, PCP, Fungal infections like Aspergillosis, CMV, Lung GVHD, Organising Pneumonia and TB.…

1
S05E05 Essential Thrombocythaemia And Polycythaemia Vera With Jon Lambert 29:25

3+ y ago29:25

29:25

Jon Lambert is a Haematologist at UCLH, and specialises in the treatment of Lymphoma and Myeloproliferative Neoplasms (MPNs). We ask him to give us insight into the presentation, diagnosis, treatment and long term impact of two common MPNs, Essential Thrombocythaemia and Polycythaemia Vera.Door Sonia Thomas, Sarah Jordan and Gavin Cooper

1
S05E04 The Liver With Deepak Suri 23:36

3+ y ago23:36

23:36

Deepak Suri is a Hepatologist and Gastroenterologist at UCLH and the Whittington. He joins us to discuss all things liver, including Hepatitis, VOD, GVHD and Haemochromatosis.Door Sonia Thomas, Sarah Jordan and Gavin Cooper

1
S05E03 T-Cell Therapies For Solid Cancers With Claire Roddie 26:28

3+ y ago26:28

26:28

In this episode we look at how T-cell based therapies are being developed for use in solid cancers. Claire Roddie is a UCLH consultant specialising in CAR T-cell treatment and discusses tumour infiltrating lymphocytes, neo-antigen receptors, checkpoint inhibitors and the barriers that need to be overcome to develop effective immunotherapy treatment…

1
S05E02 Winter Preparedness With Gee Yen Shin And Marian Salek 17:25

3+ y ago17:25

17:25

We invited back consultant virologist Gee Yen Shin and pharmacist Marian Salek to discuss the preparations being made for this winter. The conversation revolves mainly around the value of widespread uptake of the flu vaccine amongst healthcare professionals.Door Sonia Thomas, Sarah Jordan and Gavin Cooper

1
S05E01 Amyloidosis With Ashu Wechalekar 29:34

3+ y ago29:34

29:34

Dr Ashu Wechalekar joins in our first of ten episodes that will make up Series 5 of Bolus. Ashu is a renowned expert in Amyloidosis, and carries out his clinical and research work at the National Amyloidosis Centre at the Royal Free Hospital. Don't miss this comprehensive run through of this fascinating disorder.…

1
S04E07 COVID-19 Management In The ICU With Mervyn Singer 29:26

3+ y ago29:26

29:26

In our final (planned) COVID-19 episode, we are joined by intensivist Mervyn Singer, to discuss the treatments that were used in ICU for patients with severe COVID-19. In the first third we discuss the preparations that took place to get a London critical care unit ready for a pandemic. Then in the middle section, we delve into what treatments prov…

1
S04E06 Running an Intensive Care Unit Unit during COVID-19 With Elaine Thorpe 22:49

4y ago22:49

22:49

Elaine Thorpe is the UCH matron for Critical Care, one of the largest intensive care departments in the UK. We ask her to give us some insight into how her unit was prepared and reconfigured to cope with the eye of the COVID-19 storm. As increasing numbers of very unwell patients were admitted due to COVID-19, pressure on staff continued to mount. …

1
S04E05 Immunomodulatory Drugs And COVID-19 With Kwee Yong 15:09

4y ago15:09

15:09

Haematology consultant Kwee Yong joins us to discuss the immunomodulatory drugs (such as Dexamethasone, Anakinra, Tocilizumab and Ibrutinib)being evaluated as possible options to treat severe COVID-19.Door Sonia Thomas, Sarah Jordan and Gavin Cooper

1
S04E04 Thrombosis In COVID-19 With Marie Scully 13:46

4y ago13:46

13:46

UCLH Haematology consultant Marie Scully gives a concise summary of the effects COVID-19 has on coagulation and risks presented by thrombosis.Door Sonia Thomas, Sarah Jordan and Gavin Cooper

1
UCLH COVID-19 Update With Infectious Diseases Consultant Mike Brown 18:10

4y ago18:10

18:10

In this latest fascinating podcast on COVID-19, divisional clinical director and infectious diseases consultant Mike Brown talks about what UCLH has discovered so far about the novel coronavirus – identifying unusual symptoms, discovering which tests are proving to be the most useful and other important lessons learnt along the way. Mike was talkin…

1
UCLH COVID-19 Update With Marcel Levi (June 2020) 16:17

4y ago16:17

16:17

In this series of podcasts on COVID-19 with UCLH leaders, chief executive Marcel Levi reflects on the challenges we've faced over the last three months, and changes to come in the future. Marcel was interviewed by Gavin Cooper, a haematology senior clinical practice facilitator and Sarah Jordan, the ward sister of T16 South Haematology.…

1
UCLH COVID-19 Update with Consultant Virologist Gee Yen Shin 13:12

4y ago13:12

13:12

Consultant virologist Gee Yen Shin joins us to discuss why this coronavirus continues to pose particular challenges, now and in the future.Door Sonia Thomas, Sarah Jordan and Gavin Cooper

1
UCLH COVID-19 Update On Staff Testing With Laura Churchward 14:25

4y ago14:25

14:25

In the latest of a series of podcasts on COVID-19, Gavin Cooper, a haematology clinical practice facilitator and his colleague Sarah Jordan, a ward sister on T16 South, talk to UCLH director of strategy Laura Churchward about the importance of testing NHS staff for COVID-19. “If you have symptoms, please, please, please, get a test,” says Laura who…

1
UCLH COVID-19 Update on Psychological Support with Lisa Monaghan and Jane Keep 16:51

4y ago16:51

16:51

In the latest of a series of podcasts on COVID-19, Gavin Cooper, a haematology clinical practice facilitator and his colleague Sarah Jordan, a ward sister on T16 South, talk to Dr Lisa Monaghan, head of the staff psychological and welfare service, and Jane Keep, head of staff engagement and experience.…

1
UCLH COVID-19 Update with Marcel Levi (April 2020) 10:00

4y ago10:00

10:00

In the first of a series of podcasts on COVID-19 with UCLH leaders, chief executive Marcel Levi reflects on the challenges we all face in the coming weeks and how we can prepare. “(those colleagues who) work in security to those in our telephone centres – they are as important as our intensive care nurses. That is the spirit at UCLH.” Marcel was in…

1
S04E03 Blood Transfusion With Mallika Sekhar 30:07

4y ago30:07

30:07

This will be our last episode for awhile due to the COVID-19 outbreak. Mallika Sekhar joins us to discuss all things blood transfusion related. Our conversation covers the history of transfusion, antibodies, matching, infectious complications, thresholds, special requirements and more. Mallika is a Haematology Consultant specialising in Leukaemia a…

1
S04E02 Cytomegalovirus With Kirsty Thomson 29:20

4y ago29:20

29:20

Episode Two is an exploration into the issues Cytomegalovirus cause in Allogeneic Stem Cell Transplant patients. Kirsty Thomson is the Clinical Lead for UCLH Haematology and a Transplant Consultant. She guides us through the biology, screening, prophylaxis and treatment of CMV. We also discuss the issues caused by respiratory viruses in transplant …

1
S04E01 Haematopoiesis With Beth Payne 28:42

4y ago28:42

28:42

We're back with the first episode of Series 4. We're lucky to be joined by Beth Payne for a third time, as we delve into haematopoiesis and the role of the stem cell in blood production.Door Sonia Thomas, Sarah Jordan and Gavin Cooper

1
S03E10 ICU and the Haematology Patient With David Brealey And Will Townsend 38:08

4y ago38:08

38:08

The final episode of Series 3 is an interesting and wide ranging conversation on the overlap between two specialities, Haematology and Intensive Care. David Brealey is an Intensivist at UCLH and we are also rejoined by Lymphoma Consultant Will Townsend. We delve into the topics ICU staff might want to know more about in Haematology; prognosis, post…

1
S03E09 Transplant Nurse Specialists With Sarah Grace 32:00

4y ago32:00

32:00

Sarah Grace is a Transplant Clinical Nurse Specialist at UCLH. She joins us to discuss all things transplant, but with a particular focus on organising transplants, searching for and matching donors and the difficulties inherent in the consenting process.Door Sonia Thomas, Sarah Jordan and Gavin Cooper

1
S03E08 Acute Kidney Injury With Chris Laing 29:11

4y ago29:11

29:11

Joining us this week to discuss all things Acute Kidney Injury (AKI) is Chris Laing. Chris is a Consultant Nephrologist, Divisional Clinical Director for Emergency Medicine at UCLH and founder of the London AKI network.We discuss how to spot AKI in patients, both at the bedside and laboratory models that can quickly flag at risk patients. STOP crit…

1
S03E07 Acute Graft Versus Host Disease With Ronjon Chakraverty 29:26

4+ y ago29:26

29:26

In episode seven we discuss Acute Graft versus Host disease with Prof Ronjon Chakraverty, a transplant consultant at UCLH. Our conversation on aGvHD covers grading, locations, treatment and strategies to prevent it, including HLA matching, post transplant cyclophosphomide, donor lymphocyte infusions and use of steroids. We will be releasing the sec…

1
S03E06 CNS Lymphoma With Kate Cwynarski 29:12

4+ y ago29:12

29:12

For our discussion on CNS Lymphoma, we are joined by an expert in her field, Kate Cwynarski. We go through the differences between primary and secondary CNS Lymphoma, how it's diagnosed and how treatments are being improved with new clinical trial data.Door Sonia Thomas, Sarah Jordan and Gavin Cooper

1
S03E05 Secondary Immunodeficiencies With Magdalena Dziadzio and John Dempster 15:21

4+ y ago15:21

15:21

We are joined once again by Magdalena Dziadzio and John Dempster to discuss Secondary Immunodeficiencies. The immunology team supports patients following treatments such as Rituximab, CAR T-cells, Ibrutinib and autologous stem cell transplantation, due to the long term effects on their antibody production. John talks about how patients can self adm…

1
S03E04 Diamond-Blackfan Anaemia With Beth Payne 12:50

4+ y ago12:50

12:50

Welcome to Episode four of this series! We recorded a fantastic episode on MDS with Beth Payne a few months ago, and have been looking for an opportunity to release this additional part of our conversation. We had a wide ranging conversation, but initially had asked Beth to explain Diamond-Blackfan Anaemia (DBFA) to us. Our subsequent conversation …

1
S03E03 Fertility With Panos Kottaridis 24:56

4+ y ago24:56

24:56

Panos Kottaridis is a Leukaemia and Transplant consultant at UCLH, and he joins us to discuss the implications for patient's fertility that receiving treatment for a haematological condition can cause.We delve into the relative dangers posed by different chemotherapy, SACT (systemic anti-cancer therapies) and radiation to fertility, and the strateg…

1
S03E02 Myelofibrosis With Donal McLornan 31:56

4+ y ago31:56

31:56

In Episode 2 we explore the most rare of the myeloproliferative neoplasms, Myelofibrosis. Donal McLornan joins us to discuss diagnosis, patient experience and options available to treat this bone marrow scarring disease, including JAK2 inhibitors and stem cell transplantation.Door Sonia Thomas, Sarah Jordan and Gavin Cooper

1
S03E01 Bacteria With Vanya Gant 28:05

4+ y ago28:05

28:05

To kick off Series 3, we have invited pre-eminent microbiologist and clinical director for Infection at UCLH, Vanya Gant, to give us a fascinating introduction to bacteria, and it's delicate relationship with humans. Whilst bacteria is an important ally to us in health, this is always at risk of breaking down in certain circumstances. We discuss th…

1
S02E10 Sepsis With Mervyn Singer 41:02

4+ y ago41:02

41:02

Welcome to the final episode of Series 2 of Bolus. We are joined by Prof Mervyn Singer, a UCLH intensivist, researcher and teacher. He famously lead the international task force to redefine sepsis in 2016, known as Sepsis-3. Our wide ranging conversation covers a number of interesting and thought provoking questions:Is sepsis over diagnosed?Can you…

1
S02E09 Acute Patient Deterioration With Jillian 'Titch' Hartin 32:09

4+ y ago32:09

32:09

In episode 9 we are very pleased to be joined by Jillian Hartin, lead nurse for the Patient Emergency Response and Resuscitation Team (PERRT), and known to everyone as Titch.Our conversation revolves around the principles of preventing and appropriately responding to patient deterioration, which we consider on an organisational, ward and personal l…

1
S02E08 The Immune System And Primary Immunodeficiencies With Magdalena Dziadzio 20:35

4+ y ago20:35

20:35

Dr Magdalena Dziadzio kindly joins us to discuss all things immunity. She discusses the organs, tissues, proteins and cells that when combined, protect us from infection and cancer. We gain insight into how B-cell and T-cell lymphocytes work together in the thymus to develop antibodies that give our immune system memory. We then proceed onto differ…

1
S02E07 Acute Lymphoblastic Leukaemia With Adele Fielding 31:36

4+ y ago31:36

31:36

In this episode we explore the slightly less common acute leukaemia sub-type, Acute Lymphoblastic Leukaemia (ALL). Prof Adele Fielding takes us through many technical questions, why is ALL a disease seen predominantly in the young, why does it require years of maintenance therapy unlike AML, how is it diagnosed and graded, can ALL be considered a l…

1
S02E06 Aseptic Non Touch Technique (ANTT) With Stephen Rowley 30:46

4+ y ago30:46

30:46

In Episode 6 we are joined by Stephen Rowley, the senior nurse for Haematology at UCLH and the originator of Aseptic Non-Touch Technique (ANTT). Our conversation covers the role of standardisation in improving standards, the importance of having a common language when discussing asepsis, and ultimately how he has helped develop and spread the idea …

1
S02E05 Sickle Cell Disease With Perla Eleftheriou 24:34

4+ y ago24:34

24:34

In episode 5 we welcome UCLH Red Cell Consultant Perla Eleftheriou to discuss Sickle Cell Disease. She takes us through the pathophysiology of sickle cell disease (SCD) and the mainstays of current treatment including hydroxyurea and blood transfusion/red cell exchange. We look into the role allogeneic transplant can play in curing SCD, as well as …

1
S02E04 Health Informatics And Electronic Clinical Research With Wai Keong Wong 27:07

4+ y ago27:07

27:07

Welcome to Episode 4, our first ever episode not directly discussing Haematology! We are joined by Dr Wai Keong Wong, who as well as being a clinical Haematologist, is also UCLH's Chief Research Information Officer. Following the introduction of an Electronic Health Record System (EHRS) at UCLH, data is no longer technically difficult to collect, a…

1
S02E03 Multiple Myeloma With Rakesh Popat 26:53

4+ y ago26:53

26:53

This week we delve into the plasma cell disorder Multiple Myeloma, with UCLH Myeloma consultant, Dr Rakesh Popat. With incredible clarity and efficiency he covers the basics of diagnosing and treating myeloma, including the role of newer targeted therapies, allogeneic transplantation and immunotherapies. He clarifies the pathophysiology of the side…

1
S02E02 Haemostasis and Coagulation with Marcel Levi 33:36

4+ y ago33:36

33:36

We are joined in this episode by Prof Marcel Levi, the CEO of University College London Hospitals and a practicing Haematology consultant that specialises in coagulopathies, thrombosis and angioedema.This wide ranging discussion initially covers the skill of balancing clinical and managerial work, and how a medical approach to problem solving can b…

1
S02E01 Cytokine Release Syndrome and Neurotoxicity in CAR T-Cell Therapies with Claire Roddie 31:29

4+ y ago31:29

31:29

Claire Roddie leads the ever growing UCLH Immunotherapy team, caring for patients undergoing NHS funded CAR T-Cell therapy, as well as those that could be on one of the dozen different clinical trials involving CAR T-Cells. Her work has recently been featured on the BBC2 documentary 'War in the Blood' which followed two patients undergoing CAR T-Ce…

1
S01E10 POEMS and Waldenström’s Macroglobulinaemia with Shirley D'sa 31:34

5y ago31:34

31:34

In our final podcast of the series we discuss with Dr Shirley D'Sa plasma cell function and disorders including POEMS and Waldenström’s macroglobulinaemia.Dr D'sa is a haematologist with a specialist interest in Waldenström’s macroglobulinaemia and associated disorders, myeloma and POEMS syndrome at UCLH. UCLH currently manages one of the largest r…

1
S01E09 Introduction to Allogeneic Transplantation with Ben Carpenter 26:45

5y ago26:45

26:45

For our penultimate podcast of the series, we are joined by Ben Carpenter, a Transplant Consultant at UCLH. We start by discussing the history of Allogeneic transplantation through the 20th Century, and how transplants are matched. We the move into the rationale for the use of different types of conditioning and sources of haematopoietic progenitor…

1
S01E08 Myelodysplastic Syndromes with Beth Payne 21:41

5y ago21:41

21:41

Beth Payne is a Senior Clinical Researcher at the UCL Cancer Institute, where she is Research Group leader in bone marrow failure and myelodysplastic syndromes. Beth is also a Leukaemia Consultant at UCLH. The title, Myelodysplastic Syndromes (MDS), covers a diverse group of diseases, with far more genetic mutations than many Haematological disorde…

1
S01E07 Cancer Biology with Marc Mansour 33:38

5y ago33:38

33:38

Welcome to the formal launch episode of the 'Bolus' podcast!In this episode we are joined by Marc Mansour, a consultant haematologist specialising in the treatment of patients with Acute Leukaemias and Myelodyspastic Syndromes at UCLH. He is the research group leader of the Leukaemia Biology group at the UCL Cancer Institute, focusing on T-cell acu…

1
S01E06 Thrombotic Thrombocytopenic Purpura with Marie Scully 28:22

5y ago28:22

28:22

Thrombotic Thrombocytopenic Purpura (TTP) is a rare type of Microangiopathic Haemolytic Anaemia (MAHA). UCLH Haematology has long been a leading centre in the treatment of TTP, so we met up with a renowned authority on the subject, Professor Marie Scully, to discuss the disease. We run through the development of this specialism at UCLH, the disease…

1
S01E05 Thalassaemia with John Porter 20:57

5y ago20:57

20:57

Our discussion covers the background, pathophysiology and historic treatment options for patients with Thalassaemia. A new drug, LentiGlobin, has been used recently in clinical trials at UCLH. It involves genetically modifying autologous stem cells to produce sufficient Red blood cells, and takes away the need for blood transfusions.Prof John Porte…

1
S01E03 Overview of Lymphoma with Will Townsend 30:15

5y ago30:15

30:15

Dr Will Townsend is a UCLH Lymphoma Consultant and conducts Phase 1 clinical trials at the UCLH Clinical Research Facility. Our discussion covers the basics of Lymphoma, unpicking the different types, grades, classifications and treatments. At the end we touch upon a current clinical trial involving the use of T-cell Bispecific Antibodies, an off-t…

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